ID B9SDW1_RICCO Unreviewed; 921 AA.
AC B9SDW1;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=RCOM_0487570 {ECO:0000313|EMBL:EEF38195.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; EQ973932; EEF38195.1; -; Genomic_DNA.
DR RefSeq; XP_002524180.1; XM_002524134.2.
DR AlphaFoldDB; B9SDW1; -.
DR STRING; 3988.B9SDW1; -.
DR GeneID; 8274831; -.
DR KEGG; rcu:8274831; -.
DR eggNOG; KOG1052; Eukaryota.
DR InParanoid; B9SDW1; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF427; GLUTAMATE RECEPTOR 3.7; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..921
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002891351"
FT TRANSMEM 592..612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 837..859
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 473..815
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
SQ SEQUENCE 921 AA; 104185 MW; 44F4B6DBF5FEB933 CRC64;
MWVFNMRLMG KLTKLFSIIW VLLLNDFVSC QRPKFVNIGA VFTFDSVIGR VAKPAMEAAV
SDINKDTRIL NGTELKLFMV DAQCDVFLGS VGALRVLEKD VVAIIGPQSS GIAHMISQFA
NGLQVPLISY AATDPTLSAL QFPFFVRTTQ SDSYQMAAMA ELVDFYGWKE VIGIYVDDDP
GRNGINAFDD ELEKKMAKTY KLQLSVNFDE AEITGLLKKS KSLGPRVYVV HVNPDPRMRI
FTVAKKLQMM TDNYVWFATD WLSATVDSFS RINRTELSVL HGVVALRQHI PESSQKRAFV
SRWREMQQKG LVSSELNTYG LQAYDTVWAV AYAIDNFINE FKNITFPLNH ELLEMKTSEL
QLRELKIFNG GNDLLNKILQ LNFTGLSGHI QVNQDRNIES GGYDVINIVH TSVRTVGYWS
SSSGFSLLPT ETHQGEQTNY SHVDQKLQNI TWPGGKMEKP RGWEIADDER PLRIGVPRRA
SFVDFVTEVN QSHKIEGYCI DLFLEARKLI PYYVPYRFEP FGDGQSNPSY NELVRMVAED
VLDAAVGDIA IVTNRTKIVD FSQPYAASGL VILAPIRNSK SSAWVFLKPF TVEMWCVTAA
SFLMIAVVIW ILEHRVNDEF RGPPRRQIVT MFMFSFSTLF KTNQETTISP LARMVMVVWL
FVLMVITASY TASLTSILTV EQLSSPITGI DSLIASKWPI GYQVGSFAYE YLYESLYISR
SRLVPLGTPE EYERALRLGP QNVGGVAAVV DELPYVELFL AKHGDFGIIG QPFTRGGWGF
AFQRDSPLAL DMSTAILKLS ETGVLQKIHE KWFCKKGCAG EKRQKSEPNQ LRLISFWGLY
LLCGGVTLAA LLLFLLRAVR QFVHYKRRQM QQVPPSVILS TTRCSQIIFH FFDFIDKKEE
AIKKMFMQCD HPAPQVSLER S
//
