ID B9TLN3_RICCO Unreviewed; 224 AA.
AC B9TLN3;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase, putative {ECO:0000313|EMBL:EEF23232.1};
DE EC=2.3.1.168 {ECO:0000313|EMBL:EEF23232.1};
DE Flags: Fragment;
GN ORFNames=RCOM_1870520 {ECO:0000313|EMBL:EEF23232.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EQ987164; EEF23232.1; -; Genomic_DNA.
DR AlphaFoldDB; B9TLN3; -.
DR STRING; 3988.B9TLN3; -.
DR eggNOG; KOG0557; Eukaryota.
DR InParanoid; B9TLN3; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0016407; F:acetyltransferase activity; IBA:GO_Central.
DR GO; GO:0043754; F:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0031405; F:lipoic acid binding; IBA:GO_Central.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:EEF23232.1};
KW Pyruvate {ECO:0000313|EMBL:EEF23232.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW Transferase {ECO:0000313|EMBL:EEF23232.1}.
FT DOMAIN 8..222
FT /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00198"
FT NON_TER 224
FT /evidence="ECO:0000313|EMBL:EEF23232.1"
SQ SEQUENCE 224 AA; 23912 MW; 0C1207538C636141 CRC64;
MDAMTVPATV PLTGMRGAIA RNMEQGWRVP RVAQSVEVDV TALQALRAAA PEDGRVSLTA
YVLRAVALCL RDHPRLNARM REKDIELLDD VNLGLAVSLP DGLMVPVLRN ADGKSAAELG
REARTLADGA RAGTLSAGSY QRGTFTVTNL GNTDIDSFTP IINSPQVAIL GVTRVAARPV
ARGNEVAIAP LMGLHLVFDH RAVDGFPAAL FLTDLKRRLE AAKE
//
