ID B9USB6_BRAHW Unreviewed; 616 AA.
AC B9USB6;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Methyl-accepting chemotaxis protein McpB {ECO:0000313|EMBL:ACN84321.1};
DE SubName: Full=Putative bacterial sensory transduction protein {ECO:0000313|EMBL:ACH69303.1};
GN Name=mcpB {ECO:0000313|EMBL:ACN84321.1};
GN OrderedLocusNames=BHWA1_01858 {ECO:0000313|EMBL:ACN84321.1};
OS Brachyspira hyodysenteriae (strain ATCC 49526 / WA1).
OC Bacteria; Spirochaetota; Spirochaetia; Brachyspirales; Brachyspiraceae;
OC Brachyspira.
OX NCBI_TaxID=565034 {ECO:0000313|EMBL:ACH69303.1};
RN [1] {ECO:0000313|EMBL:ACN84321.1, ECO:0000313|Proteomes:UP000001803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49526 / WA1 {ECO:0000313|Proteomes:UP000001803}, and WA1
RC {ECO:0000313|EMBL:ACN84321.1};
RX PubMed=19262690; DOI=10.1371/journal.pone.0004641;
RA Bellgard M.I., Wanchanthuek P., La T., Ryan K., Moolhuijzen P.,
RA Albertyn Z., Shaban B., Motro Y., Dunn D.S., Schibeci D., Hunter A.,
RA Barrero R., Phillips N.D., Hampson D.J.;
RT "Genome sequence of the pathogenic intestinal spirochete Brachyspira
RT hyodysenteriae reveals adaptations to its lifestyle in the porcine large
RT intestine.";
RL PLoS ONE 4:E4641-E4641(2009).
RN [2] {ECO:0000313|EMBL:ACH69303.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WA1 {ECO:0000313|EMBL:ACH69303.1};
RX PubMed=18950961; DOI=10.1016/j.vetmic.2008.09.051;
RA Motro Y., La T., Bellgard M.I., Dunn D.S., Phillips N.D., Hampson D.J.;
RT "Identification of genes associated with prophage-like gene transfer agents
RT in the pathogenic intestinal spirochaetes Brachyspira hyodysenteriae,
RT Brachyspira pilosicoli and Brachyspira intermedia.";
RL Vet. Microbiol. 134:340-345(2009).
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; FJ006932; ACH69303.1; -; Genomic_DNA.
DR EMBL; CP001357; ACN84321.1; -; Genomic_DNA.
DR RefSeq; WP_012671361.1; NC_012225.1.
DR AlphaFoldDB; B9USB6; -.
DR STRING; 565034.BHWA1_01858; -.
DR KEGG; bhy:BHWA1_01858; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_12_12; -.
DR Proteomes; UP000001803; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 313..366
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 371..600
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 616 AA; 68083 MW; 5AAE09F970C6E046 CRC64;
MKRFNSITVK IPLIVNIVIV VLSFTIIFSS IQIASRAINN ATYSGFETSV NGYSTLLDTI
LEDQLIIMDA YSRVPSVIEY METRNDYIKD RAIQTMINLF DNNDYIVTLD LIGLDGKVIE
SYNGDTKNSG LDMSAAYPQL WKEFVDSGYD HATSDTIYKS DINKGFVLPI VHSVYNLENK
LIGSFIAFVD WSRIIDSTLK DTRNELSEDK TIFVVNDFDL QCVYHNINST IGINANESLM
PPEGKTSGIF SYTFNDVTRI AFFKKLNTQP WFMMAGITET LLYAESKKIT IIGTLLGVIG
IIISSIISGF YIGKSIRPIK NIVDEAHQMA DGNFVFHSTL TNRQDEIGEL SQSFDTMRNR
FVEVISEVLN ASKEIASAAS ELHKGSEDLA SRTEYQASSL EETASSMEEM ASTIKSSAQN
SVDGNEVMIA SRNAVVEGGS VIADTTKMIE DVYDASAKIK NITKVIEDIA FQTNILALNA
SVEAARAGEQ GRGFAVVASE VRNLAQNSQT SAKDITLLID DIYEKINKSA EMARHSQEIF
SDIEAKIEET SKIMSDISHT AVEQEAGVDQ VNSAVSKMDS ITQQNASLVE QSTAASKSLL
DQANHLEELM SFFKVQ
//
