ID   B9VXM5_HCMVT            Unreviewed;       850 AA.
AC   B9VXM5;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=DNA packaging terminase subunit 2 {ECO:0000313|EMBL:ACM48045.1};
GN   Name=UL56 {ECO:0000313|EMBL:ACM48045.1};
OS   Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus;
OC   Cytomegalovirus humanbeta5; Human cytomegalovirus.
OX   NCBI_TaxID=10363 {ECO:0000313|Proteomes:UP000006907};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|Proteomes:UP000006907}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Towne {ECO:0000313|Proteomes:UP000006907};
RX   PubMed=15105547; DOI=10.1099/vir.0.79888-0;
RA   Dolan A., Cunningham C., Hector R.D., Hassan-Walker A.F., Lee L.,
RA   Addison C., Dargan D.J., McGeoch D.J., Gatherer D., Emery V.C.,
RA   Griffiths P.D., Sinzger C., McSharry B.P., Wilkinson G.W., Davison A.J.;
RT   "Genetic content of wild-type human cytomegalovirus.";
RL   J. Gen. Virol. 85:1301-1312(2004).
RN   [2] {ECO:0000313|EMBL:ACM48045.1, ECO:0000313|Proteomes:UP000006907}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Towne {ECO:0000313|EMBL:ACM48045.1,
RC   ECO:0000313|Proteomes:UP000006907};
RX   PubMed=19553388; DOI=10.1099/vir.0.013250-0;
RA   Bradley A.J., Lurain N.S., Ghazal P., Trivedi U., Cunningham C.,
RA   Baluchova K., Gatherer D., Wilkinson G.W., Dargan D.J., Davison A.J.;
RT   "High-throughput sequence analysis of variants of human cytomegalovirus
RT   strains Towne and AD169.";
RL   J. Gen. Virol. 90:2375-2380(2009).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FJ616285; ACM48045.1; -; Genomic_DNA.
DR   SMR; B9VXM5; -.
DR   Proteomes; UP000006907; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016485; P:protein processing; IEA:UniProtKB-UniRule.
DR   GO; GO:0019069; P:viral capsid assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0019073; P:viral DNA genome packaging; IEA:InterPro.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04014; HSV_TRM1; 1.
DR   InterPro; IPR000501; UL28/UL56.
DR   Pfam; PF01366; PRTP; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Late protein {ECO:0000256|ARBA:ARBA00022921};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Viral genome packaging {ECO:0000256|ARBA:ARBA00023219};
KW   Viral release from host cell {ECO:0000256|ARBA:ARBA00022612};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   REGION          438..488
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          795..833
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        438..459
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   850 AA;  95756 MW;  CEEE345BC210EDC7 CRC64;
     MEMNLLQKLC VVCSKCNEYA MELECLKYCD PNVLLAESTP FKRNAAAIVY LYRKIYPEVV
     AQNRTQSSLL TLYLEMLLKA LHEDTALLDR ALMAYSRQPD RAAFYRTVLR LDRCDRHHTV
     ELQFTDNVRF SVSLATLNDI ERFLCKMNYV YGILAPEAGL EVCAQLLELL RRLCGISPVA
     RQEVYVEGTT CAQCYEELTI IPNQGRSLNK RLQGLLCNHI AVHRPSSQSD VNIQTVEQDL
     LDLTTRIPHL AGVLSALKSL FSSSSAYHSY IQEAEEALRE YNLFTDIPER IYSLSDFTYW
     SRTSEVIVKR VGITIQQLNV YHQLCRALMN GISRHLYGED VEDIFVLGEK ALDGEERMFV
     GSVFAAPNRI IDLITSLSIQ AFEDNPVFNK LHESNEMYTK IKHILEEIRR PLPDGTGGDG
     PEGEAIHLRG REAMSGTGTT LMTASNSSNS STHSQRNNGG GGRARGGGKK AVGGGANGQD
     GDGSENGLRV RNCDEHEALD LVDARSRIHN VTREVNVRKR AYLQKVSEVG YGKVIRCIKT
     QERLTSKLID VNLVGPLCLD FISKLMNGFL YRSQYHQDQD VVDVGDQFTY DEHLYVVNNL
     IHKSLPVESL PLLGQQIYEL CNGPLFTHCT DRYPLSHNVD MAYACDNAGV LPHVKDDLVK
     CAEGTVYPSE WMVVKYMGFF NFSDCQDLNV LQKEMWMHVR ELVLSVALYN ETFGKQLSIA
     CLRDELHPDR DVILTYNKEW PLLLRHEGSL YKSKDLYLLL YRHLSRPDES GDVPTAPAAK
     PSTLTAAAAV SGAFREPDRP WLPSPYPSSS TAGVSRRVRA TRKRPRRASS LLDLARDEHG
     IQDLVPGSLR
//