ID C0BZF6_9FIRM Unreviewed; 499 AA.
AC C0BZF6;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:EEG74534.1};
DE EC=4.2.3.1 {ECO:0000313|EMBL:EEG74534.1};
GN Name=thrC {ECO:0000313|EMBL:EEG74534.1};
GN ORFNames=CLOHYLEM_05196 {ECO:0000313|EMBL:EEG74534.1};
OS [Clostridium] hylemonae DSM 15053.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG74534.1, ECO:0000313|Proteomes:UP000004893};
RN [1] {ECO:0000313|EMBL:EEG74534.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG74534.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG74534.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG74534.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG74534.1}.
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DR EMBL; ABYI02000019; EEG74534.1; -; Genomic_DNA.
DR AlphaFoldDB; C0BZF6; -.
DR STRING; 553973.CLOHYLEM_05196; -.
DR eggNOG; COG0498; Bacteria.
DR HOGENOM; CLU_015170_3_1_9; -.
DR Proteomes; UP000004893; Unassembled WGS sequence.
DR GO; GO:0004795; F:threonine synthase activity; IEA:UniProtKB-EC.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:EEG74534.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51}.
FT DOMAIN 7..83
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 104..409
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 115
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 499 AA; 55620 MW; F0D9845FAE1D2269 CRC64;
MRKMNLHYKS TRNSNLKAAA SEAVLKGLAP DGGLFVPERI PALDIPMDKL KDMSYQETAY
EVMKLFLTDF TEEELKDCIG RAYDSKFDTE EIAPLTKVDD TYYLELFHGS TIAFKDMALS
ILPYLMTTAA KKNNVENEIV ILAATSGDTG KAAMAGFADV EGTRIIVFYP KNGVSRVQEL
QMVTQKGKNV DVVAIHGNFD NAQSGVKEMF ENEELAGKLA ENGYQFSSAN SINIGRLIPQ
VVYYVYAYAK LLEGEELSEG EKINVVVPTG NFGNILAAYY ARQMGVPIDH LVCASNENKV
LFDFFRTGTY DRNRDFVLTT SPSMDILISS NLERLIYLVT GEDSEQTAAF MSELKSGGSY
TLTEEMKEKL KDFKAGYATQ EQTSRQIRHI WDGTGYVLDT HTAVASYVCD EYRKTSGDSG
KCLIVSTASP FKFVKSVMTS IDSKYGEEDE FRLLEELKKV SGVEMPRAIA DILDADVLHR
TECDADKMEV TVKEILNIQ
//
