ID C0C1H6_9FIRM Unreviewed; 337 AA.
AC C0C1H6;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=3-deoxy-7-phosphoheptulonate synthase {ECO:0000313|EMBL:EEG73990.1};
DE EC=2.5.1.54 {ECO:0000313|EMBL:EEG73990.1};
GN Name=aroF {ECO:0000313|EMBL:EEG73990.1};
GN ORFNames=CLOHYLEM_05996 {ECO:0000313|EMBL:EEG73990.1};
OS [Clostridium] hylemonae DSM 15053.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG73990.1, ECO:0000313|Proteomes:UP000004893};
RN [1] {ECO:0000313|EMBL:EEG73990.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73990.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG73990.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG73990.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG73990.1}.
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DR EMBL; ABYI02000022; EEG73990.1; -; Genomic_DNA.
DR RefSeq; WP_006443343.1; NZ_GG657759.1.
DR AlphaFoldDB; C0C1H6; -.
DR STRING; 553973.CLOHYLEM_05996; -.
DR eggNOG; COG2876; Bacteria.
DR HOGENOM; CLU_062599_0_0_9; -.
DR OrthoDB; 9780456at2; -.
DR Proteomes; UP000004893; Unassembled WGS sequence.
DR GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006218; DAHP1/KDSA.
DR InterPro; IPR041071; DAHP_snth_FXD.
DR InterPro; IPR006268; DAHP_syn_2.
DR NCBIfam; TIGR01361; DAHP_synth_Bsub; 1.
DR PANTHER; PTHR43018; PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE; 1.
DR PANTHER; PTHR43018:SF1; PROTEIN AROA(G); 1.
DR Pfam; PF18152; DAHP_snth_FXD; 1.
DR Pfam; PF00793; DAHP_synth_1; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 4: Predicted;
KW Transferase {ECO:0000313|EMBL:EEG73990.1}.
FT DOMAIN 1..67
FT /note="DAHP synthase ferredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18152"
FT DOMAIN 87..330
FT /note="DAHP synthetase I/KDSA"
FT /evidence="ECO:0000259|Pfam:PF00793"
SQ SEQUENCE 337 AA; 36977 MW; 9F26367EF6E04C61 CRC64;
MIIVLKPNTK QEDVSRVEHL VKRRGLDTHI VVGQEMTIIG CIGDTTKIDA KLFEVDASVD
KVMHVQEPYK LANRAFHPED SVVDVSGVKV GRGHLALIAG PCSVESAQQV LEIAAAAKQS
GANLLRGGAF KPRTSPYSFQ GMGLDGLKIL CEAKEATGLP IVTELMSPEH LDIFNEKVDL
IQIGARNMQN FDLLKQLGQL DRPILLKRGL NATYEEWIMS AEYIMASGNE NVILCERGIR
TFETYTRNTL DLQSIPVLRK LTHLPVVVDP SHAGGKWWLV EPMAKAAIAA GADGLMVEVH
NDPESALCDG AQSLKPQKYD ELLREVTQIA KVIGKKI
//
