ID   C0C5V0_9FIRM            Unreviewed;       330 AA.
AC   C0C5V0;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Diguanylate cyclase (GGDEF) domain protein {ECO:0000313|EMBL:EEG72484.1};
GN   ORFNames=CLOHYLEM_07487 {ECO:0000313|EMBL:EEG72484.1};
OS   [Clostridium] hylemonae DSM 15053.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG72484.1, ECO:0000313|Proteomes:UP000004893};
RN   [1] {ECO:0000313|EMBL:EEG72484.1, ECO:0000313|Proteomes:UP000004893}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG72484.1,
RC   ECO:0000313|Proteomes:UP000004893};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEG72484.1, ECO:0000313|Proteomes:UP000004893}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG72484.1,
RC   ECO:0000313|Proteomes:UP000004893};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEG72484.1}.
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DR   EMBL; ABYI02000041; EEG72484.1; -; Genomic_DNA.
DR   RefSeq; WP_006444832.1; NZ_GG657761.1.
DR   AlphaFoldDB; C0C5V0; -.
DR   STRING; 553973.CLOHYLEM_07487; -.
DR   eggNOG; COG2199; Bacteria.
DR   HOGENOM; CLU_073285_0_0_9; -.
DR   OrthoDB; 9804955at2; -.
DR   Proteomes; UP000004893; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.10.450.50; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR037401; SnoaL-like.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13474; SnoaL_3; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204}.
FT   DOMAIN          194..327
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   330 AA;  38137 MW;  EC3B73DA9E70045E CRC64;
     MQTEKRLCEI TRKLWHYYML EPTEENFGKI MQTWDEKLSM IGTGRHEIFN TAEEAVKDFA
     GNQTEAGQIS FEVLDEWYNA VMIRDDVGIV YGGIWVRECR DAEAEALIEM DTRFSIVYAL
     DDSGEWKMVH IHHSMPYFDQ ADGEYYPKAL SAKVREAFEL VELFRKRSEM DLMTGIYNHD
     SFQRKTEERL MKGNQLCFYI IDLDDFKSVN DTYGHSAGDA ILKCLAKLIR KYFPEDAVVG
     RLGGDEFAVC EVCPGTQEER KERLRQMRAE YQQLSGGLLK ENPCSYSVGI AEKGKESMTY
     RQIFERADEA LYAAKQRGKD RTAELPGQGE
//