ID C0C6A9_9FIRM Unreviewed; 1427 AA.
AC C0C6A9;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Type VII secretion protein EssC {ECO:0000313|EMBL:EEG72244.1};
GN Name=essC {ECO:0000313|EMBL:EEG72244.1};
GN ORFNames=CLOHYLEM_07646 {ECO:0000313|EMBL:EEG72244.1};
OS [Clostridium] hylemonae DSM 15053.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG72244.1, ECO:0000313|Proteomes:UP000004893};
RN [1] {ECO:0000313|EMBL:EEG72244.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG72244.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG72244.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG72244.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG72244.1}.
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DR EMBL; ABYI02000042; EEG72244.1; -; Genomic_DNA.
DR RefSeq; WP_006444993.1; NZ_GG657761.1.
DR STRING; 553973.CLOHYLEM_07646; -.
DR eggNOG; COG1674; Bacteria.
DR HOGENOM; CLU_003134_2_1_9; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000004893; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR023839; Firmicutes_EssC_C.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03928; T7_EssCb_Firm; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 2.
DR PROSITE; PS50889; S4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 590..785
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 931..1116
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT COILED 1276..1303
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 611..618
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 949..956
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1427 AA; 162408 MW; 3EE93BEBEF345C5B CRC64;
MNYNLVEKDD WYEEYPQGGQ YEKVKQEGQV ISLKNEKQVF ARETCLYIGR CGNIVIDKCR
LELCIEGREV HVIGDLEKEK IYHNRKRVRD NSFLLEEGDV LLIRHTKVIL FERKIAVIGD
NKAYTSSLPE LQEPEVPFDG FPYYKRSPRI IRRIASEEAE IQAPPQKAGV SRSNLLQTLL
PPLGMMAVTV GIGLLMGRGM FLLMSVGGTG MTVIVAVIRF ISDRKERKET DKKRRKLYEQ
YLLRKRKEIY ELYRQEEEAY RYNFPPVIEI QKMVRQYSSR IYERSSSDED FLTITVGRQI
KKPAFKLRTK DNELAMNKDE LDKEASRIAA LYDWIEKECV VDLKKAHLGL VGTKAAIHEQ
LKIYISQLAA FQSYHDLQIV VVYDGRYEEE FSWMHWLPHN KIQSLNVQGL IHSERVRDQI
LNSMNQILKE RQVKLDESKK ESRFIPHFLF IIDEPKLIID HSIMEYLQGE GKNLGFSIIY
TSYLQANLPE NIGTVLLLEQ SGTGRLLLEE KELKDDKLTL QRLEGCDLEA MARDLGVLKH
IQGVTSHLPD SITFFQMYHV RRPEELDIRS RWQEGGAHKS LAVPLGVRAE DDIVYLNLHE
KAHGPHGLIA GTTGSGKSEV IQSYILSLAV NFHPYEVGFL IIDYKGGGMA NLFRDLPHLL
GTITNLDGTE SLRAMSSIRA ELKRRQRIFK DNGVNSINAY SSLFKEGKVK EPLPHLFLIS
DEFAELKKAQ PEFMKELVSV AAIGRSLGVH LILATQKPSG VVDDQIWANS RFKLALKVQN
EADSKEIIKT PDAAGITQAG RAYLQVGSNE IYELFQSAWS GADYIEEQEE EITMDDRVYL
MNELGQGVLV NRDLSGTRAE KKAKETQLDV TVRHIREVYE GEIHTEVKKP WLPSLGKKLL
SPLAAAEGRH EREEGSIVIP IGLMDVPKEQ RQTVYELNLP EDGNIMYIAS SGYGKSVFLT
TAGLSLAMSY RVRELNLYIL DFGNNALISL RNLPHTSEYI SIEDTERYDK FKELMSEEVR
YRKRRLSSVM APNFQVYNEM SEEKMRAVVV LADNFDAVKE LGFDEEEYFT RLTRDGAGVG
IYFIITASRI NAVRAATCNN FKNKLAGYNF ESGEVTNVVG RCKYKLPEIR GRAFVKREDD
VNMIQIYTMA VFEKAAEYTS NIRKLVKSIR EMYPGEEAEH IPVLPEEFSA DMMCAYEKEE
ADLYLGLEKK KVILSGFSRL CSPFFILGEG GKGKTNALKI LIEQAAGTGE VVLFDAADMG
LFGYAARKDV RYVKGLEAFI AYMDELEQEV KSREKQQRES LESTPGIAPW ETLREMPPYY
IFIDDLDNFP AYETDSIPEI AAMFRRACNA GITMIITGHT GKLKGTDELT RFVKSVADGL
MVSSQGFLGI MPVPAGADHV AFTEGLLFHN GTYKELLLPR AVERTDC
//
