ID C0C6F3_9FIRM Unreviewed; 600 AA.
AC C0C6F3;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=Aldehyde dehydrogenase (NAD) family protein {ECO:0000313|EMBL:EEG72288.1};
DE EC=1.2.1.- {ECO:0000313|EMBL:EEG72288.1};
GN ORFNames=CLOHYLEM_07690 {ECO:0000313|EMBL:EEG72288.1};
OS [Clostridium] hylemonae DSM 15053.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=553973 {ECO:0000313|EMBL:EEG72288.1, ECO:0000313|Proteomes:UP000004893};
RN [1] {ECO:0000313|EMBL:EEG72288.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG72288.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Clostridium hylemonae (DSM 15053).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG72288.1, ECO:0000313|Proteomes:UP000004893}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15053 {ECO:0000313|EMBL:EEG72288.1,
RC ECO:0000313|Proteomes:UP000004893};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG72288.1}.
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DR EMBL; ABYI02000042; EEG72288.1; -; Genomic_DNA.
DR AlphaFoldDB; C0C6F3; -.
DR STRING; 553973.CLOHYLEM_07690; -.
DR eggNOG; COG1012; Bacteria.
DR eggNOG; COG1454; Bacteria.
DR HOGENOM; CLU_007207_1_0_9; -.
DR Proteomes; UP000004893; Unassembled WGS sequence.
DR GO; GO:1990362; F:butanol dehydrogenase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07122; ALDH_F20_ACDH; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044731; BDH-like.
DR PANTHER; PTHR43633; ALCOHOL DEHYDROGENASE YQHD; 1.
DR PANTHER; PTHR43633:SF1; ALCOHOL DEHYDROGENASE YQHD; 1.
DR Pfam; PF00171; Aldedh; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EEG72288.1}.
FT DOMAIN 18..407
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT DOMAIN 464..578
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 600 AA; 65388 MW; 21C47A77563B1767 CRC64;
MAKKKEAVPA VVDSVETLGA KMKAMREAQK VFATYTQEQV DKIFYEAALA ANKMRIPLAK
QAVEETGRGI VEDKVIKNHY AAEYIYNAYK DTKTCGVIEE DKALGIKKIA EPIGLVAAVI
PTTNPTSTAI FKTLICLKTR NAIIISPHPS AKASTIAAAK IVLDAAVKAG APEGIIGWID
VPSLELTNMV MKDADIILAT GGPGMVKAAY SSGKPALGVG AGNTPVIIDD TADIRMAVNS
IIHSKTFDNG MICASEQSVT VLDSVYDEVK KEFAYRGCYF LKKGEELDKV RKTIIINGAL
NNKIPGKSAY EIARLAGVEV PEDTKILIGE VESVDISEEF AHEKLSPVLG MYRAKTFDDA
LAKAEQLVAD GGYGHTASLY VHPAEQEKIA KHAAAMKTCR ILINTPSSHG GIGDLYNFKL
APSLTLGCGS WGGNSVSENV GVKHLINIKT VAERRENMLW FRTPEKVYFK KGCMPVALDE
LGTVMKKKKA FIVTDSFLYK NGYVAPIEEK LDEMGIQHTC FYEVAPDPTL QCAQKGTDQM
KQFEPDTIIA LGGGSAMDAA KIMWVMYEHP DVNFEDMAMD FMDIRKRVYT FPKMGKKLTL
//
