ID   C0EB96_9FIRM            Unreviewed;       246 AA.
AC   C0EB96;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   SubName: Full=ThiF family protein {ECO:0000313|EMBL:EEG31316.1};
GN   ORFNames=CLOSTMETH_01114 {ECO:0000313|EMBL:EEG31316.1};
OS   [Clostridium] methylpentosum DSM 5476.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Oscillospiraceae incertae sedis.
OX   NCBI_TaxID=537013 {ECO:0000313|EMBL:EEG31316.1, ECO:0000313|Proteomes:UP000003340};
RN   [1] {ECO:0000313|EMBL:EEG31316.1, ECO:0000313|Proteomes:UP000003340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5476 {ECO:0000313|EMBL:EEG31316.1,
RC   ECO:0000313|Proteomes:UP000003340};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEG31316.1, ECO:0000313|Proteomes:UP000003340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5476 {ECO:0000313|EMBL:EEG31316.1,
RC   ECO:0000313|Proteomes:UP000003340};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Clostridium methylpentosum (DSM 5476).";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEG31316.1}.
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DR   EMBL; ACEC01000040; EEG31316.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0EB96; -.
DR   STRING; 537013.CLOSTMETH_01114; -.
DR   eggNOG; COG1179; Bacteria.
DR   HOGENOM; CLU_013325_4_1_9; -.
DR   Proteomes; UP000003340; Unassembled WGS sequence.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   CDD; cd00755; YgdL_like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   PANTHER; PTHR43267:SF1; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003340}.
FT   DOMAIN          16..241
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   246 AA;  26696 MW;  DFE29F65E30F40D6 CRC64;
     MEEFFMAHWL DRTELLIGAQ ALQRLGKARV AVIGLGGVGG ACAEAICRAG VGSLLVMDHD
     EVDITNCNRQ LFATTQTVGM DKCRAAADRL LSINPALDLI SLPQFYSEET REELFGFCPD
     FVIDAIDTVT SKLDLAQACR ERDIPLVMCM GTGNRLDPTA FRTGTIEDTA GCGCALARVM
     RRELKRRGIT GQPVVYSVEP PLKRVAQDSP QGRHSPASIS FCPPAAGYAL ASYVINQLVQ
     HNHKGD
//