ID C0EQU4_NEIFL Unreviewed; 710 AA.
AC C0EQU4;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Type IV pilus biogenesis and competence protein PilQ {ECO:0000256|ARBA:ARBA00014124};
GN Name=pilQ {ECO:0000313|EMBL:EEG32636.1};
GN ORFNames=NEIFLAOT_02342 {ECO:0000313|EMBL:EEG32636.1};
OS Neisseria flavescens NRL30031/H210.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=546264 {ECO:0000313|EMBL:EEG32636.1, ECO:0000313|Proteomes:UP000004457};
RN [1] {ECO:0000313|EMBL:EEG32636.1, ECO:0000313|Proteomes:UP000004457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRL30031/H210 {ECO:0000313|EMBL:EEG32636.1,
RC ECO:0000313|Proteomes:UP000004457};
RA Fulton L., Clifton S., Chinwalla A.T., Mitreva M., Sodergren E.,
RA Weinstock G., Clifton S., Dooling D.J., Fulton B., Minx P., Pepin K.H.,
RA Johnson M., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for type IV pilus biogenesis and competence. Could
CC function as a pore for exit of the pilus but also as a channel for
CC entry of heme and antimicrobial agents and uptake of transforming DNA.
CC {ECO:0000256|ARBA:ARBA00024678}.
CC -!- SUBUNIT: Homododecamer. Tetramer of trimer.
CC {ECO:0000256|ARBA:ARBA00025897}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|RuleBase:RU004004}.
CC -!- SIMILARITY: Belongs to the bacterial secretin family. PilQ subfamily.
CC {ECO:0000256|ARBA:ARBA00006304}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG32636.1}.
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DR EMBL; ACEN01000102; EEG32636.1; -; Genomic_DNA.
DR RefSeq; WP_003682217.1; NZ_ACEN01000102.1.
DR AlphaFoldDB; C0EQU4; -.
DR GeneID; 49972281; -.
DR eggNOG; COG4796; Bacteria.
DR Proteomes; UP000004457; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 2.60.40.3470; -; 1.
DR Gene3D; 2.60.40.3500; -; 1.
DR Gene3D; 3.30.1370.120; -; 1.
DR Gene3D; 3.30.1370.130; -; 1.
DR InterPro; IPR021731; AMIN_dom.
DR InterPro; IPR001775; GspD/PilQ.
DR InterPro; IPR005644; NolW-like.
DR InterPro; IPR038591; NolW-like_sf.
DR InterPro; IPR013355; Pilus_4_PilQ.
DR InterPro; IPR011662; Secretin/TonB_short_N.
DR InterPro; IPR004846; T2SS/T3SS_dom.
DR InterPro; IPR004845; T2SS_GspD_CS.
DR NCBIfam; TIGR02515; IV_pilus_PilQ; 1.
DR PANTHER; PTHR30604:SF1; DNA UTILIZATION PROTEIN HOFQ; 1.
DR PANTHER; PTHR30604; PROTEIN TRANSPORT PROTEIN HOFQ; 1.
DR Pfam; PF11741; AMIN; 2.
DR Pfam; PF00263; Secretin; 1.
DR Pfam; PF03958; Secretin_N; 1.
DR Pfam; PF07660; STN; 1.
DR PRINTS; PR00811; BCTERIALGSPD.
DR SMART; SM00965; STN; 1.
DR PROSITE; PS00875; T2SP_D; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Competence {ECO:0000256|ARBA:ARBA00023287};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000004457};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU004004}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..710
FT /note="Type IV pilus biogenesis and competence protein
FT PilQ"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002897621"
FT DOMAIN 303..351
FT /note="Secretin/TonB short N-terminal"
FT /evidence="ECO:0000259|SMART:SM00965"
SQ SEQUENCE 710 AA; 78103 MW; 60A36509CDC15B57 CRC64;
MKTKHMTKLF AGFSVALAVQ TAFAGNITDI NVSTLPDNQK IIKIRFDKDV TTPHGFVTST
PARIALDFAN TNIRLPQPVL EYADPLLNQI TAAQNNDRAR VVLGLNKISQ YNTEIRGNEV
WVFVNESTDQ TSAAVANERA ATPSTARAAQ TYQAVSAANI DFRKGVRNSG IIELSAPGFS
GQPDIKQQRD RVVVTLKNHT LPTQAQRSLD VADFNTPVQN VTLKRIGNST QLIIRNNNAN
WDINTKASSG RFVFEVSPKA ANTESGGLNY NANKSFKGRK ISLDFQDIEV RTILQILAKE
SGVNIVASDT VKGTMTLSLK DVPWDQALDL VMQARNLDMR RQGNIINIAP RDELLAKDKA
FLQAEKEIAE LGSLYSQTFQ LKYKNVEEFR KILRLDEYDS NNSNTRNTLL SNRGSALIDP
GTNTLIVTDN RGVIEKFRKL IDELDVPTRQ VMVEARIVEA EDTFFRNLGV KFGFVGAKGS
RAWGSNWSNA QTNYSTKFSS DRGDVDYPTW SLEPNVSLPT AAAVNSIALV RAFSSGALGL
EISASEEQGK SKTISNPRVL TQDRKEAKIE SGTEIPYQEA ASSGATSITF KKAVLGLTVT
PNITPDGQII MTVKINRDTP IDCTVDSLTT KCINTKHLNT QAMVEDGGTL IVGGIYEEES
TNAVNKVPVL GDIPVVGNLF KSRGKRENRR ELLIFITPHI MDNVGNNLRY
//
