ID C0EZ57_9FIRM Unreviewed; 1013 AA.
AC C0EZ57;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=FtsK/SpoIIIE family protein {ECO:0000313|EMBL:EEG35446.1};
GN ORFNames=EUBHAL_02713 {ECO:0000313|EMBL:EEG35446.1};
OS Anaerobutyricum hallii DSM 3353.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerobutyricum.
OX NCBI_TaxID=411469 {ECO:0000313|EMBL:EEG35446.1, ECO:0000313|Proteomes:UP000003174};
RN [1] {ECO:0000313|EMBL:EEG35446.1, ECO:0000313|Proteomes:UP000003174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3353 {ECO:0000313|EMBL:EEG35446.1,
RC ECO:0000313|Proteomes:UP000003174};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG35446.1, ECO:0000313|Proteomes:UP000003174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3353 {ECO:0000313|EMBL:EEG35446.1,
RC ECO:0000313|Proteomes:UP000003174};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Eubacterium hallii (DSM 3353).";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG35446.1}.
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DR EMBL; ACEP01000120; EEG35446.1; -; Genomic_DNA.
DR RefSeq; WP_005350135.1; NZ_ACEP01000120.1.
DR AlphaFoldDB; C0EZ57; -.
DR GeneID; 75048333; -.
DR eggNOG; COG1674; Bacteria.
DR Proteomes; UP000003174; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 665..864
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 682..689
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1013 AA; 112520 MW; 3376124698B9496E CRC64;
MASNKTNENK IKRKTTKKVT TKNNVTRKTT AKNHTSGTRK NASQKAEGIP MSSEITLVVA
FGLVVLMMFS NFGHCGLIGK WLASFFFGIF GCAQFVMPVF FFLGITILVA NDYSTLAMKK
CGAGFVILME VSAVSQLLYK DTTVTVHDLF SVAINNHATG GIIGGGVALL LREGFGTAGA
MVVLICVFLL ACILLTQRSF VSFFKKMVKN VRASKEEWEK SAEKRRLERE AAAAEDRLIN
LEEEEESSDK ATSFLKMKSG YKKTSDKKRA KQCEEKVKEL EEKKEKKNPK KQPSTSAEQE
KTIKNIKVNV PVFTSSDEVK RKDCVRELHP QIYPFTEEDG KTEPFKGKLD FSAFTFPEEN
TSLISEQAQE STLEVQEESY APPYKEKGAF HTSLPEEIRI NEDLGSLIEE VSESIVSEAE
AISEENVYPD AADQAIEQKE VPEIEAVKDM KEKQEENEES RIWKNGAEIK QRDTEAKDNA
SEVNDRDIAI QEKQMARQDT IKKETAQKVS SVESKEVVPD RKKAEGKDYL FPPASLLIKE
EQGHSSGQQQ YLQETAQKLY ETLKSFGVNV TITDISCGPS VTRYEMFPEQ GTKVSKILSL
TDDIKLNLAA SDIRIEAPIP GKAAIGIEIP NKHNQTVHFR DLIESQTFKT FKSKLAFAVG
KDIGGKTVVT DLAKMPHLLI AGATGSGKSV CINTLIMSIL YKAAPEEVKL IMIDPKMVEL
SIYNGIPHLL IPVVTDPKKA SGALNWAVAE MTNRYKKFTE TGVRNIEGYN KKVRELQKSG
EIDPETIKKM PQIVIIIDEL ADLMMVAPGE VEDAIVRLSQ LARAAGIHLV IATQRPSVNV
ITGLIKANVP SRIAFSVSSG VDSRTIIDMN GAEKLLGKGD MLFYPAGYSK PVRVQGAFIS
DNEISDVVTF LKENEDVAVY DTEVTEKIEN KLKSSAVSQE RDEYFEAAAR FVIEKDKASI
GMLQRMFKIG FNRAARIVDQ LSDAGIVGPE EGTKPRKVLM SSEQLESYFE EYL
//
