ID C0FT74_9FIRM Unreviewed; 219 AA.
AC C0FT74;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=Molybdenum transport system permease {ECO:0000256|RuleBase:RU365097};
GN Name=modB {ECO:0000313|EMBL:EEG94303.1};
GN ORFNames=ROSEINA2194_01941 {ECO:0000313|EMBL:EEG94303.1};
OS Roseburia inulinivorans DSM 16841.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=622312 {ECO:0000313|EMBL:EEG94303.1, ECO:0000313|Proteomes:UP000003561};
RN [1] {ECO:0000313|EMBL:EEG94303.1, ECO:0000313|Proteomes:UP000003561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16841 {ECO:0000313|EMBL:EEG94303.1,
RC ECO:0000313|Proteomes:UP000003561};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG94303.1, ECO:0000313|Proteomes:UP000003561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16841 {ECO:0000313|EMBL:EEG94303.1,
RC ECO:0000313|Proteomes:UP000003561};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Roseburia inulinivorans (DSM 16841).";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC molybdenum; probably responsible for the translocation of the substrate
CC across the membrane. {ECO:0000256|RuleBase:RU365097}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000256|ARBA:ARBA00007069,
CC ECO:0000256|RuleBase:RU365097}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU365097}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG94303.1}.
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DR EMBL; ACFY01000084; EEG94303.1; -; Genomic_DNA.
DR RefSeq; WP_007885702.1; NZ_JAJFOJ010000002.1.
DR AlphaFoldDB; C0FT74; -.
DR GeneID; 75163565; -.
DR eggNOG; COG4149; Bacteria.
DR Proteomes; UP000003561; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015098; F:molybdate ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR011867; ModB_ABC.
DR NCBIfam; TIGR02141; modB_ABC; 1.
DR PANTHER; PTHR30183; MOLYBDENUM TRANSPORT SYSTEM PERMEASE PROTEIN MODB; 1.
DR PANTHER; PTHR30183:SF3; MOLYBDENUM TRANSPORT SYSTEM PERMEASE PROTEIN MODB; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU365097};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505, ECO:0000256|RuleBase:RU365097};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 41..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 86..104
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 196..213
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 6..209
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 219 AA; 23729 MW; 96F89CAF5C6B89C8 CRC64;
MDFSPVWISL KTSVVSIIIT FFLGLWAARG VVSVRSTKAK AWLDGLLTLP LVLPPTVAGF
FLLYLFGAKR PAGIFLEKVF HYKIVFSWQA TVLAAVVISF PLMYRSARGA IEQVDANLIY
AGRTLGMSER TIFWKIILPQ ARPGILSGGV LAFTRGLGEF GATAMIAGNI AGKTRTLPLA
IYSEVAAGDM DTAGKYVLII VAFSLLIVAG MNLRGEKKR
//
