ID C0FYJ3_9FIRM Unreviewed; 369 AA.
AC C0FYJ3;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EEG92332.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:EEG92332.1};
GN ORFNames=ROSEINA2194_03832 {ECO:0000313|EMBL:EEG92332.1};
OS Roseburia inulinivorans DSM 16841.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=622312 {ECO:0000313|EMBL:EEG92332.1, ECO:0000313|Proteomes:UP000003561};
RN [1] {ECO:0000313|EMBL:EEG92332.1, ECO:0000313|Proteomes:UP000003561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16841 {ECO:0000313|EMBL:EEG92332.1,
RC ECO:0000313|Proteomes:UP000003561};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEG92332.1, ECO:0000313|Proteomes:UP000003561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16841 {ECO:0000313|EMBL:EEG92332.1,
RC ECO:0000313|Proteomes:UP000003561};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Roseburia inulinivorans (DSM 16841).";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEG92332.1}.
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DR EMBL; ACFY01000156; EEG92332.1; -; Genomic_DNA.
DR RefSeq; WP_009860843.1; NZ_JAJFOJ010000002.1.
DR AlphaFoldDB; C0FYJ3; -.
DR GeneID; 75164094; -.
DR eggNOG; COG0287; Bacteria.
DR Proteomes; UP000003561; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EEG92332.1}.
FT DOMAIN 8..295
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 369 AA; 41256 MW; 73BD9D140850C5DE CRC64;
MGEHDLFQKI GFIGLGLIGG SIAKKIHTLY PDVTIIATAG HQKTITEAYG EHLISNQNLC
EIKDFYDCDY IFLCTPVKRN IEYLRQLKGN IKNGCIITDV GSVKTDIHEE VTALAMEDCF
IGGHPMAGSE KTGLKNANEY LLENAYYILT PTTKTSPERL EEFRSLVTQL GAVALVLDYH
LHDYATAAIS HLPHIIAYSL VNLVKKSDDA DETMKTIAAG GFKDLTRIAS SSPVMWQNIC
QSNSEQIVRL IDAYEEMLEK TKHDILSSDA DALLQDFQSA KDYRDSIAIT NKGPIKEIYE
LYLDLLDEAG GIATVATILA SNHLSIKNIG IIHNREFEDG VLRLEMYDRI SLDAAVQLLR
KHHYTIYER
//
