ID   C0JSF7_ERIEU            Unreviewed;       239 AA.
AC   C0JSF7;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=Homeobox D12 {ECO:0000313|EMBL:ACN32421.1};
DE   Flags: Fragment;
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|EMBL:ACN32421.1};
RN   [1] {ECO:0000313|EMBL:ACN32421.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=19074008; DOI=10.1093/molbev/msn282;
RA   Wang Z., Yuan L., Rossiter S.J., Zuo X., Ru B., Zhong H., Han N., Jones G.,
RA   Jepson P.D., Zhang S.;
RT   "Adaptive evolution of 5'HoxD genes in the origin and diversification of
RT   the cetacean flipper.";
RL   Mol. Biol. Evol. 26:613-622(2009).
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis.
CC       {ECO:0000256|ARBA:ARBA00003263}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC   -!- SIMILARITY: Belongs to the Abd-B homeobox family.
CC       {ECO:0000256|ARBA:ARBA00006317}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FJ455473; ACN32421.1; -; mRNA.
DR   AlphaFoldDB; C0JSF7; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   PANTHER; PTHR46440:SF1; HOMEOBOX PROTEIN HOX-D12; 1.
DR   PANTHER; PTHR46440; HOMEOBOX PROTEIN HOX-D12-RELATED; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682}.
FT   DOMAIN          191..239
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   REGION          80..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ACN32421.1"
FT   NON_TER         239
FT                   /evidence="ECO:0000313|EMBL:ACN32421.1"
SQ   SEQUENCE   239 AA;  25253 MW;  9676804AEA3B270E CRC64;
     AGYVGSLLNL QSPDSFYFPN LRPNGGQLAA LPPISYSRGT LPWATTPASC APAQPAGATA
     FASFSQPYLT GSGPLGLQPL GPKDGPEEQA KFYTPDATAG PEERGRARLP FAPEASLGPP
     AAIKAAKYDY AGAGRAAPGS NALLEGSPCT ASFKDDAKCP LNLNMTVQAA GVASCLRPSL
     PDGLPWGAAP GRARKKRKPY TKQQIAELEN EFLLNEFINR QKRKELSNRL NLSDQQVKI
//