ID C0KJJ8_LOCMI Unreviewed; 560 AA.
AC C0KJJ8;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) {ECO:0000256|ARBA:ARBA00012728};
DE EC=5.4.2.2 {ECO:0000256|ARBA:ARBA00012728};
OS Locusta migratoria (Migratory locust).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC Acridoidea; Acrididae; Oedipodinae; Locusta.
OX NCBI_TaxID=7004 {ECO:0000313|EMBL:ACM78949.1};
RN [1] {ECO:0000313|EMBL:ACM78949.1}
RP NUCLEOTIDE SEQUENCE.
RA Tang B., Wang S.G., Zhang F., Zhang W.Q.;
RT "Characterization and expression patterns of a phosphoglucomutase from
RT Locusta migratoria.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate;
CC Xref=Rhea:RHEA:23536, ChEBI:CHEBI:58225, ChEBI:CHEBI:58601;
CC EC=5.4.2.2; Evidence={ECO:0000256|ARBA:ARBA00000443};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231, ECO:0000256|RuleBase:RU004326}.
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DR EMBL; FJ609649; ACM78949.1; -; mRNA.
DR AlphaFoldDB; C0KJJ8; -.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004614; F:phosphoglucomutase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03085; PGM1; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR Gene3D; 3.30.310.50; Alpha-D-phosphohexomutase, C-terminal domain; 1.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR016066; A-D-PHexomutase_CS.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR InterPro; IPR045244; PGM.
DR PANTHER; PTHR22573:SF2; PHOSPHOGLUCOMUTASE; 1.
DR PANTHER; PTHR22573; PHOSPHOHEXOMUTASE FAMILY MEMBER; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
DR PROSITE; PS00710; PGM_PMM; 1.
PE 2: Evidence at transcript level;
KW Magnesium {ECO:0000256|RuleBase:RU004326};
KW Metal-binding {ECO:0000256|RuleBase:RU004326}.
FT DOMAIN 16..155
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 205..297
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 308..420
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
SQ SEQUENCE 560 AA; 60686 MW; 7DFDD9CFE138E935 CRC64;
MSLNVENVKT NAFGDQKPGT SGLRKAVKVF QQPNYTENFV QSILSSLGDK LQGSTLIVGG
DGRFYCKEAV DKIIKICAAN KVSKLFVGQN GILSTPAVSA LIRTHKATGA IILTASHNPG
GPDKDFGIKF NVSNGGPAPD GVTNAIFELS KTLSSYSIVP NLKVDISKCG SQVFTVGDQK
FEVEVIDSVE HYVSYMKEIF DFNALKALIK GDITGKPFSI LINCLHGVTG PYAKQIFVKE
LGAPSDSVVN AVPLEDFGGH HPDPNLTYAA DLVNAMKAGE YDFGAAFDGD GVRNMILGKK
AFFVTPSDSL AVLAANLDCI PYSKQSGVKG FARSMPTGAA VDRVGKKLGK DVYEVPTGWK
YFGNLMDAGK LSLCGEESFG TGSDHIREKD GVWAALAWLS VIASLKKSVE EILKDHWATY
GRNYFTRYDY ENCESDPCNK MMAELETLVT SEAFKGKELS SNGRKYVVKL CDNFQFTDLI
DGSVATKQGI RVLFEDGSRI VYRLSGTGSS GATVRVYIES YEPKEYTGEP QVVLKPLISL
ALELARLQEF TGRDKPTVIT
//
