ID   C0KXY3_LEPAP            Unreviewed;       388 AA.
AC   C0KXY3;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Chalcone synthase {ECO:0000313|EMBL:ACN41945.1};
DE   Flags: Fragment;
GN   Name=CHS {ECO:0000313|EMBL:ACN41945.1};
OS   Lepidium apetalum (Pepperweed) (Lepidium micranthum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Lepidieae; Lepidium.
OX   NCBI_TaxID=153459 {ECO:0000313|EMBL:ACN41945.1};
RN   [1] {ECO:0000313|EMBL:ACN41945.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=19254769; DOI=10.1016/j.ympev.2009.02.015;
RA   Joly S., Heenan P.B., Lockhart P.J.;
RT   "A Pleistocene inter-tribal allopolyploidization event precedes the species
RT   radiation of Pachycladon (Brassicaceae) in New Zealand.";
RL   Mol. Phylogenet. Evol. 51:365-372(2009).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
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DR   EMBL; FJ645112; ACN41945.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0KXY3; -.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF14; CHALCONE SYNTHASE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          10..233
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          244..388
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        169
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
FT   NON_TER         388
FT                   /evidence="ECO:0000313|EMBL:ACN41945.1"
SQ   SEQUENCE   388 AA;  42273 MW;  96EA982C519D4287 CRC64;
     MVMAGSSSLD EIRKAQRADG PAGILAIGTA NPENHVIQAE YPDYYFRITN SEHMTDLKEK
     FQRMCDKSMI RKRHMHLTED LLKENPNMCA YMAPSLDARQ DIVVVEVPKL GKEAAVKAIK
     EWGQPKSKIT HVVFCTTSGV DMPGADYQLT KLLGLRPSVK RLMMYQQGCF AGGTVLRLAK
     DLAENNRGAR VLVVCSEITA VTFRGPSDTH LDSLVGQALF SDGAAALIVG SDPDTSVGEK
     PIFEMVSAAQ TILPDSDGAI DGHLREVGLT FHLLKDVPGL ISKNIEKSLD EAFKPLGISD
     WNSLFWVAHP GGPAILDQVE IKLGLKAEKM RATRHVLSEY GNMSSACVLF ILDEMRRKSA
     KDGVATTGEG LEWGVLFGFG PGLTVETV
//