ID C0L365_HHV1 Unreviewed; 227 AA.
AC C0L365;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Truncated thymidine kinase {ECO:0000313|EMBL:ACN54642.1};
OS Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Orthoherpesviridae; Alphaherpesvirinae; Simplexvirus;
OC Simplexvirus humanalpha1.
OX NCBI_TaxID=10298 {ECO:0000313|EMBL:ACN54642.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:ACN54642.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=R14A:185Fs-228St {ECO:0000313|EMBL:ACN54642.1};
RX PubMed=19795980; DOI=10.1086/606028;
RA Duan R., de Vries R.D., van Dun J.M., van Loenen F.B., Osterhaus A.D.,
RA Remeijer L., Verjans G.M.;
RT "Acyclovir susceptibility and genetic characteristics of sequential herpes
RT simplex virus type 1 corneal isolates from patients with recurrent herpetic
RT keratitis.";
RL J. Infect. Dis. 200:1402-1414(2009).
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DR EMBL; FJ655159; ACN54642.1; -; Genomic_DNA.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004797; F:thymidine kinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006230; P:TMP biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001889; Herpes_TK.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00693; Herpes_TK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ACN54642.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ACN54642.1}.
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 227 AA; 24339 MW; 6D424590EE051E6D CRC64;
MASYPGHQHA SAFDQAARSR GHSNRRTALR PRRQQEATEV RPEQKMPTLL RVYIDGPHGM
GKTTTTQLLV ALGSRDDIVY VPEPMTYWQV LGASETIANI YTTQHRLDQG EISAGDAAVV
MTSAQITMGM PYAVTDAVLA PHIGGEAGSS HAPPPALTLI FDRHPIAALL CYPAARYLMG
SMTPPGRAGV RGPHPADLAR HKHRVGGPSG GQTHRPPGQT PAPRRAA
//
