ID C0M6C0_STRE4 Unreviewed; 231 AA.
AC C0M6C0;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=GntR family regulatory protein {ECO:0000313|EMBL:CAW93924.1};
GN OrderedLocusNames=SEQ_1207 {ECO:0000313|EMBL:CAW93924.1};
OS Streptococcus equi subsp. equi (strain 4047).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=553482 {ECO:0000313|EMBL:CAW93924.1, ECO:0000313|Proteomes:UP000001365};
RN [1] {ECO:0000313|EMBL:CAW93924.1, ECO:0000313|Proteomes:UP000001365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4047 {ECO:0000313|EMBL:CAW93924.1,
RC ECO:0000313|Proteomes:UP000001365};
RX PubMed=19325880; DOI=10.1371/journal.ppat.1000346;
RA Holden M.T.G., Heather Z., Paillot R., Steward K.F., Webb K., Ainslie F.,
RA Jourdan T., Bason N.C., Holroyd N.E., Mungall K., Quail M.A., Sanders M.,
RA Simmonds M., Willey D., Brooks K., Aanensen D.M., Spratt B.G., Jolley K.A.,
RA Maiden M.C.J., Kehoe M., Chanter N., Bentley S.D., Robinson C.,
RA Maskell D.J., Parkhill J., Waller A.S.;
RT "Genomic evidence for the evolution of Streptococcus equi: host
RT restriction, increased virulence, and genetic exchange with human
RT pathogens.";
RL PLoS Pathog. 5:E1000346-E1000346(2009).
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DR EMBL; FM204883; CAW93924.1; -; Genomic_DNA.
DR RefSeq; WP_012679585.1; NC_012471.1.
DR AlphaFoldDB; C0M6C0; -.
DR KEGG; seu:SEQ_1207; -.
DR HOGENOM; CLU_017584_5_4_9; -.
DR OrthoDB; 9781630at2; -.
DR Proteomes; UP000001365; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RSPR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..85
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 231 AA; 27050 MW; C8C77418F836C227 CRC64;
MNPIIEAVKN NLDLSRNIPL KIAFYNALKK TIILRQIPAG SRINEKEFSI ALNISRTPIR
YALGLLSEEH LVEHIPKKGI IVKGVSIQDA CEIFEIRKAL ETLATSTAMY LMTEEDFQVM
HDLLADCETF IEDDDLNRIL DNFNSFNNLI YSYSQMVRLK EIVTELQTYL VYFRKISISS
LERRKRALSE HWMIYRGMKN RDHEQITLIT HEHLNSSLEF ILQEMSRRQD D
//
