ID C0N243_9GAMM Unreviewed; 632 AA.
AC C0N243;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=HAMP domain protein {ECO:0000313|EMBL:EEF81311.1};
GN ORFNames=MDMS009_303 {ECO:0000313|EMBL:EEF81311.1};
OS Methylophaga thiooxydans DMS010.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=637616 {ECO:0000313|EMBL:EEF81311.1, ECO:0000313|Proteomes:UP000004679};
RN [1] {ECO:0000313|EMBL:EEF81311.1, ECO:0000313|Proteomes:UP000004679}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMS010 {ECO:0000313|EMBL:EEF81311.1,
RC ECO:0000313|Proteomes:UP000004679};
RX PubMed=21478352; DOI=10.1128/JB.00388-11;
RA Boden R., Ferriera S., Johnson J., Kelly D.P., Murrell J.C., Schafer H.;
RT "Draft genome sequence of the chemolithoheterotrophic, halophilic
RT methylotroph Methylophaga thiooxydans DMS010.";
RL J. Bacteriol. 193:3154-3155(2011).
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DR EMBL; GG657883; EEF81311.1; -; Genomic_DNA.
DR RefSeq; WP_008290095.1; NZ_GG657883.1.
DR AlphaFoldDB; C0N243; -.
DR HOGENOM; CLU_000445_109_1_6; -.
DR OrthoDB; 5894408at2; -.
DR Proteomes; UP000004679; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.110.200; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 6.20.270.20; LapD/MoxY periplasmic domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR032244; LapD_MoxY_N.
DR InterPro; IPR042461; LapD_MoxY_peri_C.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF16448; LapD_MoxY_N; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 172..224
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 263..392
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 399..632
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 632 AA; 70888 MW; 830C9074E077CACB CRC64;
MSLSKQLLIL ISLIFLIVFS VSFLLSMSNI RNYLEVESEI HVQDTATSLG LSLSPHMSDE
QDPILQTMMN AIFDMGYYKE MRLENVDGEN LVKLTNPVQM EGVPSWIIQL LPMQPATAVS
EISSGWTISG TIHVSSNPAY AYLKLYEQAK ETLLYSFLIF LAAFALLMLV LRFTLKPLKD
IQKQANEIST GNFTTITQLP WTREVRQVAT SMNGMSKKIG DTIARLNSRL DSLNDSLKRD
LLTGLFNQPT FDVDVKKAMS ASQTGYAIYI KFDDLAEISK DKGNDVVDTL LREFAQTLKQ
CVANHGDAYR LYGSEFALLC PEADEKTITV LADKLKQDVT HLGQRYDIED MVHTGIVLFD
RSSEFDRLMP AMIEAYEQAR IIGLNAYFIK QDSISSRSEQ EWKAIIHQTI DNNTPEITFT
AEAFNYSGAA PVKVMQEAFT VVTDSDGMQL PIGTFFSMAQ EFNQAEMLDR CIINKIIHKM
EQADQQVPVT INLSMVSVAS AEFHAWLSAR LEQTTLANNL LAFSVTAYAA AKDLAAFASF
SSFVKNLGAT TLLKRYSSDI ITTDMLRELH IDYIRLSRNV TENIRGNVNK PDFIEIIQEV
ASLVEIKVLA ESVKADDDFE FVKQAGLYGI SR
//
