ID C0N435_9GAMM Unreviewed; 324 AA.
AC C0N435;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=LysR substrate binding domain protein {ECO:0000313|EMBL:EEF80574.1};
GN ORFNames=MDMS009_899 {ECO:0000313|EMBL:EEF80574.1};
OS Methylophaga thiooxydans DMS010.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=637616 {ECO:0000313|EMBL:EEF80574.1, ECO:0000313|Proteomes:UP000004679};
RN [1] {ECO:0000313|EMBL:EEF80574.1, ECO:0000313|Proteomes:UP000004679}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMS010 {ECO:0000313|EMBL:EEF80574.1,
RC ECO:0000313|Proteomes:UP000004679};
RX PubMed=21478352; DOI=10.1128/JB.00388-11;
RA Boden R., Ferriera S., Johnson J., Kelly D.P., Murrell J.C., Schafer H.;
RT "Draft genome sequence of the chemolithoheterotrophic, halophilic
RT methylotroph Methylophaga thiooxydans DMS010.";
RL J. Bacteriol. 193:3154-3155(2011).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; GG657892; EEF80574.1; -; Genomic_DNA.
DR RefSeq; WP_008290638.1; NZ_GG657892.1.
DR AlphaFoldDB; C0N435; -.
DR HOGENOM; CLU_039613_6_2_6; -.
DR OrthoDB; 5297026at2; -.
DR Proteomes; UP000004679; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08443; PBP2_CysB; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF6; HTH-TYPE TRANSCRIPTIONAL REGULATOR CYSB-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004679};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..57
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 324 AA; 36355 MW; 53411BAE01E92033 CRC64;
MKLQQIKYLV GIVTNDLNVS KTADKFFTSQ PGVSRQIKLL EEELNVDIFE RNGRLLTGLT
PVGNAILEMA SEVLDRVNNI KSVAKEFSEE ISGKLTIATT HTQARYVLPR TIIHFTNMHE
SVGFQLKQGN PHQAFEMVSK GMVDFAIASE AMDDFSNLIT FPCYSWNRLV LVKRDHPLAS
GAPISIEQLS KYPLVTYENG FTGRYQLNNA FQKAGLEPNI MLTASDADII KAYVKMDLGV
GVIASVAYDP DDDCDLVSIN VRELFDDCVA KIAIRKGVSL RSYMYDFIEL FSPHLSRDIV
ERTLAKPSSE EVFSIMDKLD IPHY
//
