ID   C0NJD1_AJECG            Unreviewed;       759 AA.
AC   C0NJD1;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=U-box domain-containing protein {ECO:0000313|EMBL:EEH07972.1};
GN   ORFNames=HCBG_03261 {ECO:0000313|EMBL:EEH07972.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH07972.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG663366; EEH07972.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NJD1; -.
DR   STRING; 447093.C0NJD1; -.
DR   VEuPathDB; FungiDB:I7I50_06822; -.
DR   HOGENOM; CLU_013635_0_0_1; -.
DR   InParanoid; C0NJD1; -.
DR   OrthoDB; 5488722at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR036844; Hint_dom_sf.
DR   InterPro; IPR039510; Vint_dom.
DR   InterPro; IPR032838; Vwaint_dom.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF14623; Vint; 1.
DR   Pfam; PF00092; VWA; 1.
DR   Pfam; PF14624; Vwaint; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          75..271
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   759 AA;  83652 MW;  8FE48C8E60B35533 CRC64;
     MDPVQPAASS EDDFEIIDDQ IPIRPRLSTS TTIAGERSPN EVGVQLHPLP DTNSMILSVH
     PPLHPEKEMP HVPCDIVLCI DVSYSMQSSA PLPTTDESGE REETGLSVLD LTKHAARTII
     ETLNENDRLG IVAFSTEAEV VYKISKMNES NKKAALKAVE ALKPLSSTNL WHGLKLGLKA
     FENERHTLQS VQALYVLTDG MPNHMCPKQG YVTKLRPILQ LLGHRMPMIH TFGFGYNIRS
     GLLQAIAEVG GGTFAFIPDA GMIGTVFVHA IANLYTTFAT QAKVTFQTSG SVTLAQELGS
     KTGLGLHEES TKDSNLTVAI GTLQYGQSRD LVIRTKNATT AATPSMAQAT LTYQFQGRLK
     SVVSDEQVLS QRTSLPVHVS DYHLSRARIC AFLRSLYPLG PDKEYTNIDE NGLKNARQQL
     DHIIKDIKQL EHTDEENDSL VRDLAGEEPE GQLRLSILVH ANFAKWGKHY LLSLLNAHTH
     QMCNSFKDPG PLQYGKNSPF FCRCREELDT CFDNLPPPKP SIIEKSPDGT VKIRPSYKMS
     RYNCRNNPCF AGHCNIRLAE RNSSLPIRDI RAGIKVWTPL GPRRVRAVLA TAVKNTILCN
     IGSLSITPWH PIQVAGDWIF PSHVSEQNVP FSGTVYSVLL DPSPVSDAHA IMVEGHVCVS
     LGHGIQGCND VRAHPFFGSY PSVLRSLASL PRDVNGILRC SGMKRNPLTG LACGFIGEGG
     FRKSINKRPF KRSAKVGLRY HFQAPITVNP RRRTACPAF
//