ID C0NSV9_AJECG Unreviewed; 579 AA.
AC C0NSV9;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=HCBG_06239 {ECO:0000313|EMBL:EEH05120.1};
OS Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS (Darling's disease fungus) (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH05120.1, ECO:0000313|Proteomes:UP000001631};
RN [1] {ECO:0000313|Proteomes:UP000001631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC {ECO:0000313|Proteomes:UP000001631};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RENT3 family.
CC {ECO:0000256|ARBA:ARBA00005991}.
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DR EMBL; GG663371; EEH05120.1; -; Genomic_DNA.
DR AlphaFoldDB; C0NSV9; -.
DR STRING; 447093.C0NSV9; -.
DR VEuPathDB; FungiDB:I7I50_05944; -.
DR HOGENOM; CLU_018549_1_0_1; -.
DR InParanoid; C0NSV9; -.
DR OrthoDB; 77197at2759; -.
DR Proteomes; UP000001631; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd12455; RRM_like_Smg4_UPF3; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR039722; Upf3.
DR InterPro; IPR005120; UPF3_dom.
DR PANTHER; PTHR13112:SF0; FI21285P1; 1.
DR PANTHER; PTHR13112; UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF03467; Smg4_UPF3; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001631};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 433..499
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..261
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..376
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 61431 MW; CAF1EBBD9EDCB41F CRC64;
MAPHSPKPSS AGVLPISPLA AQRGSSNKPS PKPAAPQLKV LIRRLPPGLT AQEFVAVLGD
EWKVGNGKVD WFRFKEGKVF KDPAKPSRPT RAYLRVTSIP LVDELSEKVR VSAFQDGRNT
SRDPILLGPP SLEYAPYPRV PGSRVRKDGR QGTIDLDSDF ITFLESLTNP VTKSVADIAA
DDTREEKPTI TPLIQFLKEK RANKGKETSS PARPSRHSRG EAREGKDAKV ERVHARKLLS
RAEKATPSPG DRPKIERATK QSIKAVNKQT ANQMSKKPRK ASESLSPKEE RPPPTVIAPE
RRRERGSMSA ATKILRRDLG LAPAAPRRRA EKLANSATTE PPLTGEADGA PVHSNEDGSK
RTSTKASKEA ESTRKPALAK QAKGALQPSA VTGRNTSKSA NRPVTPTTVT VSSVSKHNPT
LASAQAVPHS TATQAFLKHA NPSQGVTEEL LVAGFATFGK VVKVEIDKKK GFGYVDFAEP
GGLAKAIQAS PVQIAQSQVV VLERKSGAAV AQARVNASNR PSQSTMGSAP RVVSSGGGQT
PSRPTRRGNR GKGGSKETGV GGGNAGSNAG GGNKIGTSK
//
