ID   C0NTD0_AJECG            Unreviewed;       327 AA.
AC   C0NTD0;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Cyclase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HCBG_06410 {ECO:0000313|EMBL:EEH05291.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH05291.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Cyclase 1 superfamily.
CC       {ECO:0000256|ARBA:ARBA00007865}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GG663371; EEH05291.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NTD0; -.
DR   STRING; 447093.C0NTD0; -.
DR   VEuPathDB; FungiDB:I7I50_05698; -.
DR   HOGENOM; CLU_030671_1_1_1; -.
DR   InParanoid; C0NTD0; -.
DR   OrthoDB; 2076300at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   GO; GO:0004061; F:arylformamidase activity; IEA:InterPro.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:InterPro.
DR   Gene3D; 3.50.30.50; Putative cyclase; 1.
DR   InterPro; IPR007325; KFase/CYL.
DR   InterPro; IPR037175; KFase_sf.
DR   PANTHER; PTHR34861; -; 1.
DR   PANTHER; PTHR34861:SF8; -; 1.
DR   Pfam; PF04199; Cyclase; 1.
DR   SUPFAM; SSF102198; Putative cyclase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
SQ   SEQUENCE   327 AA;  36432 MW;  9408F96760342342 CRC64;
     MAQISPFDIP FDKLPNPRQV WVGAPGSLEE GLGKISLLTP EVVAEAAAEI KTGVRVTLGW
     EMTKLELANL NRQPCQHHII SLLNGLAFDD VYIMNPQQSS QWDGLRHFSQ PVPDTDGKSA
     ERVFYGGTTA SEILNRSNDR IGMQYWARQG ITGRGVLIDY ASYATKRGIK YSTFSTHQIR
     LSDILEISAD CNLTFKRGDI LFIRIGVTNE WDNVMTDDQK RAYSVNPKPE HAGVEATTEM
     LRWLWDTGFS AVAGDAISWE VYPPQNPDIF LHEYLLAGWG VPIGELFDLE TLSHTCQELG
     RWTFFLSSVP LNMPGGVSSP PNAIAIF
//