ID   C0NZM0_AJECG            Unreviewed;       229 AA.
AC   C0NZM0;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=HORMA domain-containing protein {ECO:0000313|EMBL:EEH03268.1};
GN   ORFNames=HCBG_08600 {ECO:0000313|EMBL:EEH03268.1};
OS   Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)
OS   (Darling's disease fungus) (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=447093 {ECO:0000313|EMBL:EEH03268.1, ECO:0000313|Proteomes:UP000001631};
RN   [1] {ECO:0000313|Proteomes:UP000001631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432
RC   {ECO:0000313|Proteomes:UP000001631};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA   Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain G186AR.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the MAD2 family.
CC       {ECO:0000256|ARBA:ARBA00010348}.
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DR   EMBL; GG663378; EEH03268.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0NZM0; -.
DR   STRING; 447093.C0NZM0; -.
DR   VEuPathDB; FungiDB:I7I50_00050; -.
DR   HOGENOM; CLU_072097_0_0_1; -.
DR   InParanoid; C0NZM0; -.
DR   OrthoDB; 5474106at2759; -.
DR   Proteomes; UP000001631; Unassembled WGS sequence.
DR   Gene3D; 3.30.900.10; HORMA domain; 1.
DR   InterPro; IPR003511; HORMA_dom.
DR   InterPro; IPR036570; HORMA_dom_sf.
DR   InterPro; IPR045091; Mad2-like.
DR   PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR   PANTHER; PTHR11842:SF11; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; 1.
DR   Pfam; PF02301; HORMA; 1.
DR   SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR   PROSITE; PS50815; HORMA; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001631}.
FT   DOMAIN          16..223
FT                   /note="HORMA"
FT                   /evidence="ECO:0000259|PROSITE:PS50815"
FT   REGION          113..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..142
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   229 AA;  25771 MW;  BDE0EBF8C8D1B4F9 CRC64;
     MSTQKEKSKV HKLSLKGSSK LVAEFFEYSI HSILFQRGVY PADDFTAVKK YGLNMLVSSD
     DQVKAYIKKI MSQLNKWMIG GKISKLVIVI TSKDTGEHVE RWQFDVQIFN NGRSSRNRST
     QKASPDNENA PIPTNTAATT PPPEKSEKEI QEEIQAIFRQ ITASVTFLPV LDGNCTFNVL
     VYADADSEVP MEWGDSDAKE IENGEKVQLR SFSTSNHRVD TLVSYRLAD
//