ID C0RGI5_BRUMB Unreviewed; 626 AA.
AC C0RGI5;
DT 05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 05-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=DEAD-box ATP-dependent RNA helicase ydbR {ECO:0000313|EMBL:ACN99942.1};
GN OrderedLocusNames=BMEA_A0131 {ECO:0000313|EMBL:ACN99942.1};
OS Brucella melitensis biotype 2 (strain ATCC 23457).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=546272 {ECO:0000313|EMBL:ACN99942.1, ECO:0000313|Proteomes:UP000001748};
RN [1] {ECO:0000313|Proteomes:UP000001748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23457 {ECO:0000313|Proteomes:UP000001748};
RA Setubal J.C., Boyle S., Crasta O.R., Gillespie J.J., Kenyon R.W., Lu J.,
RA Mane S., Nagrani S., Shallom J.M., Shallom S., Shukla M., Snyder E.E.,
RA Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Munk C., Tapia R.,
RA Han C., Detter J.C., Bruce D., Brettin T.S.;
RT "Brucella melitensis ATCC 23457 whole genome shotgun sequencing project.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
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DR EMBL; CP001488; ACN99942.1; -; Genomic_DNA.
DR RefSeq; WP_004686661.1; NC_012441.1.
DR AlphaFoldDB; C0RGI5; -.
DR KEGG; bmi:BMEA_A0131; -.
DR HOGENOM; CLU_003041_21_3_5; -.
DR Proteomes; UP000001748; Chromosome I.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProt.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd12252; RRM_DbpA; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR005580; DbpA/CsdA_RNA-bd_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR PANTHER; PTHR47959:SF19; ATP-DEPENDENT RNA HELICASE DBPA; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF03880; DbpA; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492}.
FT DOMAIN 31..207
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 234..408
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 432..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..626
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 68862 MW; 1254402AB3FB583F CRC64;
MSLPDTIAPT LSGALTARGY NTLTAVQNAV LAPETLASDL LVSAQTGSGK TVAFGLAMAN
TILEDELRFG DAGAPLAMII APTRELALQV RRELEWLYAD TGARIASCVG GMDIRTERRA
LERGSHIVVG TPGRLRDHIT RNALDMSQLR AIVLDEADEM LDMGFREDLE FILGEAPEDR
RTLMFSATVP KPIAQLAKRF QNNALRITVQ SETSQHADID YVAMPVPPHE RDHAIINTLL
YYDSQNSIIF CSTREAVKHM ASRLSNRGFA VVALSGELSQ AERNNALQAM RDGRARVCVA
TDVAARGIDL PNLDLVIHAD LPTNPDTLLH RSGRTGRAGR KGTCVLVVPF SRRRSAERLL
HMAKLDAQTV PAPSIAAVQA KTNERILNAE VFNQPVEEEY QELLKALAER YTPEQIASAF
LNREVASYPA AEEVSDAPVH PVGGKKPRSD RFEKGDRYER GERRERGEPG ERFDRNARFD
GVWFSVSAGR KHRADPKWLL PLICKAGDVS KRDVGSIKIF DNETRFEIAA SKADEFRQSV
AERGTGEKSL VIRTAVTGAG GDAAARESRG SFKPRSDKFK EGGFRDGHKT DKPRDFSRGD
DFKKDGFKKG GKKSEGGGYS KKRRGE
//
