ID   C0RLX4_BRUMB            Unreviewed;       851 AA.
AC   C0RLX4;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   RecName: Full=DEAD/H associated domain protein {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=BMEA_B0805 {ECO:0000313|EMBL:ACO02607.1};
OS   Brucella melitensis biotype 2 (strain ATCC 23457).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=546272 {ECO:0000313|EMBL:ACO02607.1, ECO:0000313|Proteomes:UP000001748};
RN   [1] {ECO:0000313|Proteomes:UP000001748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23457 {ECO:0000313|Proteomes:UP000001748};
RA   Setubal J.C., Boyle S., Crasta O.R., Gillespie J.J., Kenyon R.W., Lu J.,
RA   Mane S., Nagrani S., Shallom J.M., Shallom S., Shukla M., Snyder E.E.,
RA   Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Munk C., Tapia R.,
RA   Han C., Detter J.C., Bruce D., Brettin T.S.;
RT   "Brucella melitensis ATCC 23457 whole genome shotgun sequencing project.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001489; ACO02607.1; -; Genomic_DNA.
DR   RefSeq; WP_004682186.1; NC_012442.1.
DR   AlphaFoldDB; C0RLX4; -.
DR   GeneID; 29595288; -.
DR   KEGG; bmi:BMEA_B0805; -.
DR   HOGENOM; CLU_002025_0_1_5; -.
DR   Proteomes; UP000001748; Chromosome II.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18796; SF2_C_LHR; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR026362; DEXH_lig_assoc.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR017170; Lhr-like_ATP-dep_RNA_helic_prd.
DR   InterPro; IPR045628; Lhr_WH_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR04121; DEXH_lig_assoc; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   PANTHER; PTHR47962:SF3; LARGE ATP-DEPENDENT HELICASE-RELATED PROTEIN; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF19306; Lhr_WH; 1.
DR   PIRSF; PIRSF037307; Lhr-like_helic_prd; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          39..237
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          271..421
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   851 AA;  94453 MW;  38366C8D74674004 CRC64;
     MTLTRKPIAA SATFLLPDRF VKWFAAKGWS PRAHQLELLA RAEQGQSTLL IAPTGAGKTL
     AGFLPALVDL EKRRSKAISG KVGTGFPSGI APKSKSGVHT LYISPLKALA VDIRRNLTVP
     VEEMGLDISI ETRTGDTPAH KRQRQKLAPP DILLTTPEQL ALLIASRVAE QFFKDLRYVV
     LDELHSLVIS KRGHLLALGL ARLRRLQPQL QTIGLSATVA EPDELRRWLV EQDGTGSMAG
     LVTVDGGAKP EITILDSKER VPWAGHSSRY AIPDIYAAIR QHRTTLLFVN TRSQAEMLFQ
     ELWRVNEETL PIALHHGSLD AGQRRKVEQA MAANTLRAVV ATSTLDLGID WGDVDLVIHV
     GAPKGASRLA QRIGRANHRM DEPSRAILVP ANRFEVMECR AALDANYLGA QDTPPLIDGA
     LDVLAQHVLG MACAEPFNAD QLYREVQSAA PYANLPRDTF DRILDFVATG GYALKTYERF
     AKIRKTVDGT WRVSNPRIAQ QYRLNIGTIV EAPELNVRLT RGGKGANARG GRVLGRIEEY
     FLETLTAGDT FLFAGKVLRF EGIRENECIA SNAAGQDAKI PVYAGGKFPL STYLAAQVRA
     MLADRARWQF LPQQVREWLE VQQWKSVLPG TDELLIETFP RGNRFYMVAY PFEGRLAHQT
     LGMLLTRRLE RMGAHPLGFV TTDYSLGLWG LKDMASMIRM GRLNLSRLFD EDMLGDDLEA
     WLDESYLLKR TFRNCAVISG LIERRHPGQE KTGRQVTVST DLIYDVLRSH EPDHILLQAT
     RADAATGLLD IKRLGDMLAR VKGHILHKPL DQISPLALPV MLEIGRERVA GEGDEMLLEE
     AADDLVREAM Q
//