ID C0WFG2_9CORY Unreviewed; 594 AA.
AC C0WFG2;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:EEI15583.1};
GN ORFNames=HMPREF0276_0198 {ECO:0000313|EMBL:EEI15583.1};
OS Corynebacterium accolens ATCC 49725.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=525260 {ECO:0000313|EMBL:EEI15583.1, ECO:0000313|Proteomes:UP000003641};
RN [1] {ECO:0000313|EMBL:EEI15583.1, ECO:0000313|Proteomes:UP000003641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49725 {ECO:0000313|EMBL:EEI15583.1,
RC ECO:0000313|Proteomes:UP000003641};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEI15583.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACGD01000001; EEI15583.1; -; Genomic_DNA.
DR RefSeq; WP_005280077.1; NZ_GG666998.1.
DR AlphaFoldDB; C0WFG2; -.
DR GeneID; 81674970; -.
DR eggNOG; COG3276; Bacteria.
DR HOGENOM; CLU_023030_3_0_11; -.
DR Proteomes; UP000003641; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; SelB-wing_3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EEI15583.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000313|EMBL:EEI15583.1}.
FT DOMAIN 1..171
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 594 AA; 63828 MW; 5DB16BA32DC0D3F5 CRC64;
MYVIATAGHV DHGKSSLVRA LTDMDPDRWA EEKRRGLTID LGFVWTALPS GADVAFVDVP
GHEKFFGNML AGVGPASVVL FVVAADEGWQ AQSTDHRDAL HALGIEHGVI ALTRSDRADE
KRRAEVTAQV RTQFSATPLA DAPIIPVSSH TGEGLAELGA ALDDLVARVP APDTDAPVRL
WIDRAFSVKG AGTVVTGTLS AGTLRTGDAL VLSTAAGDKR VEIRGLHSEN TAQESLGPVT
RAAVNLRGVD AADIHRGDLL LTPGAWRGVD IVDVHRTFGT ALDELPDNLV VHCGTAGIEA
HLRPLSADFA RLRLSRALPL VILDRLVVRS PGGRHVSAGV EVIDVRPPEL DRRGAARKRA
EALAEHTSFR NPSSYLQRVG YARRADLELD GYDTDATPPG IINFHQWWIA ARQVTRWKET
LTTALQEHAA ANPLAPGMPR NAALDALGLK EEGLLRLAVA AAHAEESEGL IRLPGHTVDL
GAAEPAVAEL ERRLETEPFA APEAHELKEL GLSEKELAAA ERAGRLLRLK DGIILLPDAP
DKAREHLSQL EQPFTLSAAR QVLGTTRRVA IPLLEYLDAQ GITRRGEGGK RTLR
//
