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Database: UniProt
Entry: C1A893_GEMAT
LinkDB: C1A893_GEMAT
Original site: C1A893_GEMAT 
ID   C1A893_GEMAT            Unreviewed;       592 AA.
AC   C1A893;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   05-JUL-2017, entry version 54.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   OrderedLocusNames=GAU_1411 {ECO:0000313|EMBL:BAH38453.1};
OS   Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC
OS   100505).
OC   Bacteria; Gemmatimonadetes; Gemmatimonadales; Gemmatimonadaceae;
OC   Gemmatimonas.
OX   NCBI_TaxID=379066 {ECO:0000313|EMBL:BAH38453.1, ECO:0000313|Proteomes:UP000002209};
RN   [1] {ECO:0000313|Proteomes:UP000002209}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T-27 / DSM 14586 / JCM 11422 / NBRC 100505
RC   {ECO:0000313|Proteomes:UP000002209};
RA   Takasaki K., Ichikawa N., Miura H., Matsushita S., Watanabe Y.,
RA   Oguchi A., Ankai A., Yashiro I., Takahashi M., Terui Y., Fukui S.,
RA   Yokoyama H., Tanikawa S., Hanada S., Kamagata Y., Fujita N.;
RT   "Complete genome sequence of Gemmatimonas aurantiaca T-27 that
RT   represents a novel phylum Gemmatimonadetes.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; AP009153; BAH38453.1; -; Genomic_DNA.
DR   RefSeq; WP_012682900.1; NC_012489.1.
DR   ProteinModelPortal; C1A893; -.
DR   STRING; 379066.GAU_1411; -.
DR   EnsemblBacteria; BAH38453; BAH38453; GAU_1411.
DR   KEGG; gau:GAU_1411; -.
DR   eggNOG; COG0593; LUCA.
DR   OrthoDB; POG091H000O; -.
DR   BioCyc; GAUR379066:GI3W-1430-MONOMER; -.
DR   Proteomes; UP000002209; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 2.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002209};
KW   DNA replication {ECO:0000256|RuleBase:RU004227};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002209}.
FT   DOMAIN       37    171       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      417    559       AAA. {ECO:0000259|SMART:SM00382}.
SQ   SEQUENCE   592 AA;  64994 MW;  87E19DA48318B409 CRC64;
     MTSALDRKLR FDTFVVGGSN RLAASAARAV ADAPGQAYNP LFVYGESGRG KTHLVAAIAN
     RAQENQPDLR VLFSSGEEVA EHLHQSIASG QPQRFLEHYQ QADLLILDDV QFLTGQRETQ
     SELLRLLNVL MRAGQQLVFT SDRQPADIPD VDQRLLSRLS GGLVVDVGSP DFEMRLAILR
     NVAVERRTDF ASGVLDEVAR LPFANVRELK GALNKLSAYQ QLEGQPVKAD DVRAIVGERS
     TAPATTPGGS LAVGTRSSPL PGRIEAIIPA GTDYEGFLAD VLNEVESRVE PWRVKLGDAI
     AHWRQMGYVV RVLERAVALP TAPDVDGLLN AYGVAVERLR QLEHHAGSLD ASLRGHAAFR
     NPEAIPAAQA LVQEAIAAAL PLPAPSPVFT RESLQISTGN QLALRAVDAV LEEPGRRYNP
     LLLHGPSGSG KSHTVHAIGN AMKQADGRRA VACLSAGTFV EEFVAAMQEG GVERWRARYR
     AADVFILDDI QELVGKERTQ DELFHLFNHL VNRGSQVVLT SDRIPRDLNG FADRLRSRFE
     GGLVVALPAR ERVRVEQLVA RAPGELDRFY EDREKTMWEW PDLGSRLIEE YR
//
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