ID   PTH_RHOOB               Reviewed;         190 AA.
AC   C1AY15;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   01-MAY-2013, entry version 29.
DE   RecName: Full=Peptidyl-tRNA hydrolase;
DE            Short=PTH;
DE            EC=3.1.1.29;
GN   Name=pth; OrderedLocusNames=ROP_57630;
OS   Rhodococcus opacus (strain B4).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Corynebacterineae; Nocardiaceae; Rhodococcus.
OX   NCBI_TaxID=632772;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B4;
RA   Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA   Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Comparison of the complete genome sequences of Rhodococcus
RT   erythropolis PR4 and Rhodococcus opacus B4.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The natural substrate for this enzyme may be peptidyl-
CC       tRNAs which drop off the ribosome during protein synthesis (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: N-substituted aminoacyl-tRNA + H(2)O = N-
CC       substituted amino acid + tRNA.
CC   -!- SUBUNIT: Monomer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the PTH family.
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DR   EMBL; AP011115; BAH54010.1; -; Genomic_DNA.
DR   RefSeq; YP_002782955.1; NC_012522.1.
DR   STRING; 632772.ROP_57630; -.
DR   EnsemblBacteria; BAH54010; BAH54010; ROP_57630.
DR   GeneID; 7746324; -.
DR   KEGG; rop:ROP_57630; -.
DR   PATRIC; 23228887; VBIRhoOpa21106_5814.
DR   eggNOG; COG0193; -.
DR   HOGENOM; HOG000004796; -.
DR   KO; K01056; -.
DR   OMA; SEFINDF; -.
DR   ProtClustDB; PRK05426; -.
DR   BioCyc; ROPA632772:GH0Q-7063-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004045; F:aminoacyl-tRNA hydrolase activity; IEA:HAMAP.
DR   GO; GO:0006412; P:translation; IEA:HAMAP.
DR   Gene3D; 3.40.50.1470; -; 1.
DR   HAMAP; MF_00083; Pept_tRNA_hydro_bact; 1; -.
DR   InterPro; IPR001328; Pept_tRNA_hydro.
DR   InterPro; IPR018171; Pept_tRNA_hydro_CS.
DR   PANTHER; PTHR17224; PTHR17224; 1.
DR   Pfam; PF01195; Pept_tRNA_hydro; 1.
DR   SUPFAM; SSF53178; Pept_tRNA_hydro; 1.
DR   TIGRFAMs; TIGR00447; pth; 1.
DR   PROSITE; PS01195; PEPT_TRNA_HYDROL_1; FALSE_NEG.
DR   PROSITE; PS01196; PEPT_TRNA_HYDROL_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Hydrolase.
FT   CHAIN         1    190       Peptidyl-tRNA hydrolase.
FT                                /FTId=PRO_1000118405.
SQ   SEQUENCE   190 AA;  20352 MW;  F53A3AB283B88EDE CRC64;
     MSEDTALVVG LGNPGPQYEK TRHNVGFMVA GVLSARMGGK FSAHKKSGAE IVQGRLEGRP
     TILAKPRSFM NLSGSAVAGL ARFFSVDPGN IVVIHDELDL DFGTIRLKQG GGEGGHNGLR
     SISQSLGTKD YLRTRVGIGR PPGRMDPASY VLKPFSSVER KELDLVCEES ADAVELVLRL
     GLEAAQNRLH
//