ID C1BH40_ONCMY Unreviewed; 71 AA.
AC C1BH40;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Guanine nucleotide-binding protein subunit gamma {ECO:0000256|RuleBase:RU004973};
GN Name=GBG2 {ECO:0000313|EMBL:ACO08343.1};
GN Synonyms=gbg2 {ECO:0000313|Ensembl:ENSOMYP00000057397.1}, GNG2
GN {ECO:0000313|Ensembl:ENSOMYP00000131765.1};
GN ORFNames=GSONMT00035606001 {ECO:0000313|EMBL:CDQ85253.1},
GN GSONMT00080258001 {ECO:0000313|EMBL:CDQ59640.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:ACO08343.1};
RN [1] {ECO:0000313|EMBL:ACO08343.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=White blood cell {ECO:0000313|EMBL:ACO08343.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Yasuike M., von Schalburg K., Cooper G., Leong J., Davidson W.S.,
RA Koop B.F.;
RT "Oncorhynchus mykiss ESTs and full-length cDNAs from White Blood Cells.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDQ59640.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [3] {ECO:0000313|EMBL:CDQ59640.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|Ensembl:ENSOMYP00000057397.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC as a modulator or transducer in various transmembrane signaling
CC systems. The beta and gamma chains are required for the GTPase
CC activity, for replacement of GDP by GTP, and for G protein-effector
CC interaction. {ECO:0000256|RuleBase:RU004973}.
CC -!- SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma.
CC {ECO:0000256|RuleBase:RU004973}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU004973};
CC Lipid-anchor {ECO:0000256|RuleBase:RU004973}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU004973}.
CC -!- SIMILARITY: Belongs to the G protein gamma family.
CC {ECO:0000256|ARBA:ARBA00007431, ECO:0000256|RuleBase:RU004973}.
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DR EMBL; BT073919; ACO08343.1; -; mRNA.
DR EMBL; BT073948; ACO08372.1; -; mRNA.
DR EMBL; FR904329; CDQ59640.1; -; Genomic_DNA.
DR EMBL; FR906716; CDQ85253.1; -; Genomic_DNA.
DR RefSeq; NP_001158576.1; NM_001165104.1.
DR STRING; 8022.C1BH40; -.
DR PaxDb; 8022-C1BH40; -.
DR Ensembl; ENSOMYT00000062481.2; ENSOMYP00000057397.1; ENSOMYG00000026471.2.
DR Ensembl; ENSOMYT00000121412.1; ENSOMYP00000131765.1; ENSOMYG00000075053.1.
DR GeneID; 100305200; -.
DR KEGG; omy:100305200; -.
DR CTD; 100305200; -.
DR GeneTree; ENSGT01100000263497; -.
DR OrthoDB; 2872810at2759; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR Proteomes; UP000694395; Chromosome 19.
DR Proteomes; UP000694395; Chromosome 25.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IEA:InterPro.
DR GO; GO:0031681; F:G-protein beta-subunit binding; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00068; GGL; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR001770; Gprotein-gamma.
DR PANTHER; PTHR13809:SF25; GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-2; 1.
DR PANTHER; PTHR13809; GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT; 1.
DR Pfam; PF00631; G-gamma; 1.
DR PRINTS; PR00321; GPROTEING.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR PROSITE; PS50058; G_PROTEIN_GAMMA; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU004973};
KW Lipoprotein {ECO:0000256|RuleBase:RU004973};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004973};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU004973}.
FT DOMAIN 5..71
FT /note="G protein gamma"
FT /evidence="ECO:0000259|PROSITE:PS50058"
SQ SEQUENCE 71 AA; 7852 MW; F450D02435B7A37A CRC64;
MASNNTASIA QARKLVEQLK MEANIDRIKV SKAAADLMSY CEAHAKEDPL LSPVPASENP
FREKKFFCAI L
//
