ID   C1C9Y2_STRP7            Unreviewed;      1161 AA.
AC   C1C9Y2;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Cell wall surface anchor family protein {ECO:0000313|EMBL:ACO17525.1};
GN   OrderedLocusNames=SP70585_0145 {ECO:0000313|EMBL:ACO17525.1};
OS   Streptococcus pneumoniae (strain 70585).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=488221 {ECO:0000313|EMBL:ACO17525.1, ECO:0000313|Proteomes:UP000002211};
RN   [1] {ECO:0000313|Proteomes:UP000002211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70585 {ECO:0000313|Proteomes:UP000002211};
RX   PubMed=21034474; DOI=10.1186/gb-2010-11-10-r107;
RA   Donati C., Hiller N.L., Tettelin H., Muzzi A., Croucher N.J.,
RA   Angiuoli S.V., Oggioni M., Dunning Hotopp J.C., Hu F.Z., Riley D.R.,
RA   Covacci A., Mitchell T.J., Bentley S.D., Kilian M., Ehrlich G.D.,
RA   Rappuoli R., Moxon E.R., Masignani V.;
RT   "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and
RT   closely related species.";
RL   Genome Biol. 11:R107.1-R107.19(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000918; ACO17525.1; -; Genomic_DNA.
DR   RefSeq; WP_000671388.1; NC_012468.1.
DR   AlphaFoldDB; C1C9Y2; -.
DR   KEGG; snm:SP70585_0145; -.
DR   HOGENOM; CLU_008941_0_0_9; -.
DR   Proteomes; UP000002211; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR021021; Fibronectin-binding_SSURE.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR005877; YSIRK_signal_dom.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   NCBIfam; NF038031; PavB_Nterm; 1.
DR   NCBIfam; TIGR01168; YSIRK_signal; 1.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   Pfam; PF11966; SSURE; 6.
DR   Pfam; PF04650; YSIRK_signal; 1.
DR   PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1135..1154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1125..1161
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|PROSITE:PS50847"
FT   REGION          39..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1059..1099
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..55
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..106
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..126
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1161 AA;  123384 MW;  C3F6EA6FE716BCA3 CRC64;
     MKFNPNQRYT RWSIRRLSVG VASVVVASGF FVLVGQPSSV RADGLNPTPG QVLPEETSGT
     KEGDLSEKPG DTVLTQAKPE GVTGNTNSLP TPTERTEVSE ETSPSSLDTL FEKDEEAQKN
     PELTDVLKET VDTADVDGTQ ASPAETTPEQ VKGGVKENTK DSIDVPAAYL EKAEGKGPFT
     AGVNQVIPYE LFAGDGMLTR LLLKASDNAP WSDNGTAKNP ALPPLEGLTK GKYFYEVDLN
     GNTVGKQGQA LIDQLRANGT QTYKATVKVY GNKDGKADLT NLVATKNVDI NINGLVAKET
     VQKAVADNVK DSIDVPAAYL EKAKGEGPFT AGVNHVIPYE LFAGDGMLTR LLLKASDKAP
     WSDNGDAKNP ALSPLGENVK TKGQYFYQVA LDGNVAGKEK QALIDQFRAN GTQTYSATVN
     VYGNKDGKPD LDNIVATKKV TININGLISK ETVQKAVADN VKDSIDVPAA YLEKAKGEGP
     FTAGVNHVIP YELFAGDGML TRLLLKASDK APWSDNGDAK NPALSPLGEN VKTKGQYFYQ
     VALDGNVAGK EKQALIDQFR ANGTQTYSAT VNVYGNKDGK PDLDNIVATK KVTININGLI
     SKETVQKAVA DNVKDSIDVP AAYLEKAKGE GPFTAGVNHV IPYELFAGDG MLTRLLLKAS
     DKAPWSDNGD AKNPALSPLG ENVKTKGQYF YQVALDGNVA GKEKQALIDQ FRANGTQTYS
     ATVNVYGNKD GKPDLDNIVA TKKVTINING LISKETVQKA VADNVKDSID VPAAYLEKAK
     GEGPFTAGVN HVIPYELFAG DGMLTRLLLK ASDKAPWSDN GDAKNPALSP LGENVKTKGQ
     YFYQVALDGN VAGKEKQALI DQFRANGTQT YSATVNVYGN KDGKPDLDNI VATKKVTINI
     NGLISKETVQ KAVADNVKDS IDVPAAYLEK AKGEGPFTAG VNHVIPYELF AGDGMLTRLL
     LKASDKAPWS DNGDAKNPAL SPLGENVKTK GQYFYQVALD GNVAGKEKQA LIDQFRANGT
     QTYSATVNVY GNKDGKPDLD NIVATKKVTI KINVKETSDT ANGSLSPSNS GSGVTPMNHN
     HATGTTDSMP ADTMTSSTNT MAGENMAASA NKMSDTMMSE DKAMLPNTGE TQTSMASIGF
     LGLALAGLLG GLGLKNKKEE N
//