ID C1DTM0_SULAA Unreviewed; 564 AA.
AC C1DTM0;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN OrderedLocusNames=SULAZ_0465 {ECO:0000313|EMBL:ACN98851.1};
OS Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825).
OC Bacteria; Aquificota; Aquificae; Aquificales; Hydrogenothermaceae;
OC Sulfurihydrogenibium.
OX NCBI_TaxID=204536 {ECO:0000313|EMBL:ACN98851.1, ECO:0000313|Proteomes:UP000001369};
RN [1] {ECO:0000313|EMBL:ACN98851.1, ECO:0000313|Proteomes:UP000001369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Az-Fu1 / DSM 15241 / OCM 825
RC {ECO:0000313|Proteomes:UP000001369};
RX PubMed=19136599; DOI=10.1128/JB.01645-08;
RA Reysenbach A.L., Hamamura N., Podar M., Griffiths E., Ferreira S.,
RA Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A.,
RA Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.;
RT "Complete and draft genome sequences of six members of the Aquificales.";
RL J. Bacteriol. 191:1992-1993(2009).
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
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DR EMBL; CP001229; ACN98851.1; -; Genomic_DNA.
DR RefSeq; WP_012674171.1; NC_012438.1.
DR AlphaFoldDB; C1DTM0; -.
DR STRING; 204536.SULAZ_0465; -.
DR KEGG; saf:SULAZ_0465; -.
DR eggNOG; COG1196; Bacteria.
DR eggNOG; COG1418; Bacteria.
DR HOGENOM; CLU_028328_1_0_0; -.
DR OrthoDB; 9803205at2; -.
DR Proteomes; UP000001369; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000001369};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}.
FT DOMAIN 380..473
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 23..235
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 564 AA; 64560 MW; C32ACCD43FAD14C3 CRC64;
MNEVIVGLLS AVFAGGAGFT ACKVMVEKKL KEKEEEYNKV LSRKEEIEKL AKEEAERIKK
EAEKEVERIL KEAEREAKIR ASEIEKEALK LKEQQEFIIE KELLKRKQEL ENEIRQKREE
LQNLEKQLLM RESQLEKRLA RLEHREEEIE KRAAEIAKLE SEIKALEKQL KEKEEKLKSA
EEHYILELQR IASMTKEEAK AELMRKVEEE AKLEAAKLMR EIEEEAKKNA EKEAKWTLVT
AIQRLAPEAT TTYTVSVVDL PSNDIKGRII GREGRNIRAF EMATGVDLII DDTPDIVTIS
SFDPLRREIA KIALERLIAD GRIHPGRIEE VVEKVKEEMD QHIRKLGEET CLELGFTDVH
PELYYYIGKL NYRTSYTQNV LLHTKEVAYL AGMMAAMLGL DEKMARRGGL MHDIGKAISH
EVGGAHSKVG AEIAKRYGEP DYVINAILYH HGDEPARYPE AVLVAAADAL SAARPGARRE
VLQSYINRLE KIEAIVNSFE NVEKSFAIQA GREVRVIVNA EKLSDEEAYL LTKEIAKRIE
KEVEFPGQIK VVTIRESRFV EVAK
//
