ID C1DUW9_SULAA Unreviewed; 488 AA.
AC C1DUW9;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Putative serine protease MucD {ECO:0000313|EMBL:ACN99687.1};
GN OrderedLocusNames=SULAZ_0933 {ECO:0000313|EMBL:ACN99687.1};
OS Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825).
OC Bacteria; Aquificota; Aquificae; Aquificales; Hydrogenothermaceae;
OC Sulfurihydrogenibium.
OX NCBI_TaxID=204536 {ECO:0000313|EMBL:ACN99687.1, ECO:0000313|Proteomes:UP000001369};
RN [1] {ECO:0000313|EMBL:ACN99687.1, ECO:0000313|Proteomes:UP000001369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Az-Fu1 / DSM 15241 / OCM 825
RC {ECO:0000313|Proteomes:UP000001369};
RX PubMed=19136599; DOI=10.1128/JB.01645-08;
RA Reysenbach A.L., Hamamura N., Podar M., Griffiths E., Ferreira S.,
RA Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A.,
RA Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.;
RT "Complete and draft genome sequences of six members of the Aquificales.";
RL J. Bacteriol. 191:1992-1993(2009).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
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DR EMBL; CP001229; ACN99687.1; -; Genomic_DNA.
DR AlphaFoldDB; C1DUW9; -.
DR STRING; 204536.SULAZ_0933; -.
DR MEROPS; S01.453; -.
DR KEGG; saf:SULAZ_0933; -.
DR eggNOG; COG0265; Bacteria.
DR HOGENOM; CLU_020120_1_0_0; -.
DR Proteomes; UP000001369; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:ACN99687.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001369};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 273..362
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 371..453
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 122
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 152
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 232
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 488 AA; 52852 MW; 41F31F16D43B8720 CRC64;
MKRFVLPVLI ILGLAFFVKA QFGKFQEGYK QNVEGKSYSF PTLEAIDNER TKLIESVSPG
VATVFTTQEI TVNNPFFDMP FGDFFGIPNT PQFKQKRQGL GSAFIVDVDY NKKVVYLLTN
NHVVENAKDI QVQFKNKMIL KGKVVGGDKL SDVAVLEVPF KKGIEDFASK NVLKLGDSDQ
LKVGSTVIAI GAPLGLSDTV TIGIVSAKNR QIEDRPGEGF IQTDAAINPG NSGGPLINVR
GEVVGINTAI IAGAQGLGFA VPINQAKWVM DQILKYGKVK RSKIGVVIQP LTADLAEHFG
VNEGALVSSV QPGGPADKAG IKAGDIIVEV NGKKISDISD LQNQVMKNPP GSKLKIKVIR
DGKELTFDVV TVPLESDETA STEESGQAAN IESAIGLIVK DITPELIKRY GLPKVDYGVL
VYAVKEGSVA EEAGLQAGDI ILSVNKKPVR SASEFWQIIS KAKNEKQDNV LLYIQRRDNR
IYTTLPLR
//
