ID C1E5F1_MICCC Unreviewed; 1058 AA.
AC C1E5F1;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=ATP-dependent helicase HrpB {ECO:0008006|Google:ProtNLM};
GN ORFNames=MICPUN_58293 {ECO:0000313|EMBL:ACO63248.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO63248.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO63248.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001326; ACO63248.1; -; Genomic_DNA.
DR RefSeq; XP_002501990.1; XM_002501944.1.
DR AlphaFoldDB; C1E5F1; -.
DR STRING; 296587.C1E5F1; -.
DR GeneID; 8243277; -.
DR KEGG; mis:MICPUN_58293; -.
DR eggNOG; KOG0923; Eukaryota.
DR InParanoid; C1E5F1; -.
DR OMA; VCYRLWD; -.
DR OrthoDB; 3685484at2759; -.
DR Proteomes; UP000002009; Chromosome 5.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17990; DEXHc_HrpB; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010225; HrpB.
DR InterPro; IPR049614; HrpB_DEXH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013689; RNA_helicase_ATP-dep_HrpB_C.
DR NCBIfam; TIGR01970; DEAH_box_HrpB; 1.
DR PANTHER; PTHR43519; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR PANTHER; PTHR43519:SF1; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF08482; HrpB_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009}.
FT DOMAIN 76..227
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 279..448
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 577..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..593
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1058 AA; 111225 MW; 02344AA2E5A79E03 CRC64;
MSSVHASASA LAWRGVVGQH RVDRARPPTR RGGRSIASGR RVATVSCEAG EARAIDPRLD
AVVDSLPIRE VLYRCLDALD ESTGLVLQAP PGAGKTTALP LAMILSNPAW LPRTGKVIVL
EPRRLAARAA ATRMASILNE PVGKTVGYSV RFESKVSPAT RVEVVTEGVL VRRLQRDPSL
DGVFAIVFDE FHERSLDADV ALALASETRS ALRPDLRLVV MSATLGDVGP RASEMLSRGD
GGPSCPLLVS EGKSFPVETV YLGPPGRNFG DLEDATVAAV RRALSDAPGV DGGDVLCFLP
GAAEINRVVA ALRDGQSESL SVLPLYGALG QAEQQAALAP APGGTRRVVV STPIAESSLT
IPGVRIVVDS GLARRPRFDS NKGMTRLDTA LISVASADQR RGRAGRVAPG TCYRLWSERT
HAQLASDAEP EIANADLAPL ALDLATWGIR DDEGVTSLPW LDPPPAGRLS AARDLLTRLG
ATEEGTGRVT PLGERMARLP LHPRLARMVL WGASRGPESC RMACQIAAVL SDRDLLRGRD
APADVRARLG ALWSLGDGGA DGPGLARWSL EARAAEPTPA VPPSTPKAPI DPAAPVRVPI
GTKLPKGKNK GGKFKGAPKG RRPAGGGVQA AAKAARAAAS SAGAGSSSAS SVGGFGAAYG
GYRGFEIDRN ATREAGKVVS QLLNAVKVLA ADDGGEWCAP GVGGGDPRGP CWDFLLGEGE
NEAGVLLAVA YPDRVGVRRS KGGNFQLSGG VGAASVPGSD PLARAEVLAI AEMTSGDVGG
GARNDRVRLA APVPLTALEP DGDRPGCLAD ALCRRRDSVS WASASKAVVA RRQLCVGDAV
LRESPFQPTP DETVEAMLCG VKEMGVRAAL GWSDKTESWR RRVMWLRTAG GADHLPDLSD
AALEATLDDW LAPMLPGVTS KSAMHKQLDG DGLVRCLLTY EQTMEVDQSC PTHVVVPSGS
RLPLDYDTPG GTPVLRARLQ ELFGMAETPT IGPKRVPIEV HLLSPASRPV QVTTDLASFW
KNTYFDVAKE LKGRYPKHYW PDDPTTAVAT NRAKPRSK
//
