ID C1EAH4_MICCC Unreviewed; 892 AA.
AC C1EAH4;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=P-type ATPase superfamily {ECO:0000313|EMBL:ACO64860.1};
GN ORFNames=MICPUN_60072 {ECO:0000313|EMBL:ACO64860.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO64860.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO64860.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|RuleBase:RU362081}.
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DR EMBL; CP001328; ACO64860.1; -; Genomic_DNA.
DR RefSeq; XP_002503602.1; XM_002503556.1.
DR AlphaFoldDB; C1EAH4; -.
DR STRING; 296587.C1EAH4; -.
DR GeneID; 8244893; -.
DR KEGG; mis:MICPUN_60072; -.
DR eggNOG; KOG0207; Eukaryota.
DR InParanoid; C1EAH4; -.
DR OMA; YPTYFGY; -.
DR OrthoDB; 317296at2759; -.
DR Proteomes; UP000002009; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00371; HMA; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF19; COPPER-TRANSPORTING ATPASE PAA2, CHLOROPLASTIC; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01047; HMA_1; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 194..216
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 262..279
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 815..834
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 846..864
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 56..124
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT REGION 579..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 892 AA; 89113 MW; 707CB98F19C8A1C8 CRC64;
MPTGMFGWRG KHLGRIGGAG TYSRQLWSPP RASGATLAEE GVSSAVNRQE EENEGSTILF
TVEGMRCGGC SAAVQKVLVA TPGVSRAAVN LVTETAAVEL AAGASESTIA EFTKAVGDKG
FTMSPRPVGR AAEEAAIKAE ARRAEEMERT KWDLYKAWGL TGLCLVTHTT HHLHHFGLHE
YAHGELLTAL GQPWVGGAIA VLALAGPGAG IMREGFKALA NGAPNMNSLV GVGASAAFAL
SIAGALAPPV IGDYGVPVNN DFFEEPVLLL AFILLGRALE SRARARAASD LRSLSTLLPL
DARLVVADKL PEVGDDSDPM TVSVDRLALR PGDLVRVLPG EVIPVDGEVV SGAAAVDEAT
LTGEPLLVPK AGGDQVSAGT GVFEGPLTVR ATTAGDGSVA AGIARTVADA QARAAPVQRL
ADAVAGPFVY GVMAASATTF AFWNFAGDAF FPGALLEASG GAGATLGALK LATDVLVVAC
PCALGLATPT AVLVATSAGA RLGLLLRGGD VLEASAQIDT VALDKTGTIT EGKPRVTGVA
CASDELTSAD VLRLAAAVES TTTHPLAAAV EEAATAAVTA DRGPHNTLPR ADDAETSPGR
GAAANVEGKR VYVGNPEWVE SQVGAPAGSA AALSAAAADN SEATGGPAAA ACSLVAVGIE
GEGIIGAIAL ADKIRPGAAG AVRRLVDMGL KVVILSGDRQ PAVDAIAQEL GLGGSVVAKG
GLLPADKEAF VKGLQERGAK VAMVGDGIND APALVAADVG MAVSGGMEAT AQAAGVVLLG
DKDDGKSGVA GGGVGQAADA IELGRSALSK IRQNLGWALA YNLVGIPVAA GVLLPEYGIS
LNPAAAGAMM ALSSVAVVTN SLLLKVPGGV ERAGAPGDGL IKRPSARPAP AR
//
