ID C1FF12_MICCC Unreviewed; 696 AA.
AC C1FF12;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Acyl-CoA-binding protein {ECO:0000313|EMBL:ACO68667.1};
GN Name=ACBP {ECO:0000313|EMBL:ACO68667.1};
GN ORFNames=MICPUN_54790 {ECO:0000313|EMBL:ACO68667.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO68667.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO68667.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SIMILARITY: Belongs to the ACBP family.
CC {ECO:0000256|ARBA:ARBA00005567}.
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DR EMBL; CP001574; ACO68667.1; -; Genomic_DNA.
DR RefSeq; XP_002507409.1; XM_002507363.1.
DR AlphaFoldDB; C1FF12; -.
DR STRING; 296587.C1FF12; -.
DR GeneID; 8249958; -.
DR KEGG; mis:MICPUN_54790; -.
DR eggNOG; KOG0379; Eukaryota.
DR eggNOG; KOG0817; Eukaryota.
DR InParanoid; C1FF12; -.
DR OMA; RTCTWSM; -.
DR OrthoDB; 52705at2759; -.
DR Proteomes; UP000002009; Chromosome 1.
DR GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR000582; Acyl-CoA-binding_protein.
DR InterPro; IPR035984; Acyl-CoA-binding_sf.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011498; Kelch_2.
DR PANTHER; PTHR46093:SF3; ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46093; ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00887; ACBP; 1.
DR Pfam; PF07646; Kelch_2; 1.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF47027; Acyl-CoA binding protein; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR PROSITE; PS51228; ACB_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 7..94
FT /note="ACB"
FT /evidence="ECO:0000259|PROSITE:PS51228"
FT REGION 131..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 614..648
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 162..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 74091 MW; 9A36F57C628EEF5C CRC64;
MAHKLPFPDR FYAAVGFAAN PPLGSRAVSD ETRLLLYALY QQVTAGPCTT PKPFWNQLER
AKWNSWNSLG SLSTIDAMRM YVSGIEDENP DWYDLVTNDG DEERVREVAE AAAEAVAAAG
MDAKAQLARL DDRGDGGQKD QPSPRTPGPP PAGRRSLGRS PRPSADNLTQ SVSRSSLSSR
DPPLDPAVAK IPCLEDGTWT DVTYAVGGAK PRGRSGHASV RIGASEVWTV GGVRNGRRIA
DVCVFDTIKM EWASDDELRC SMKPGEVDVA HLTGWPARSG HAAVAFGTKI LVIGGHTRED
DPVDAQCEVW VLETTSREWS RLKVEGDAPC ARGGHTATMV EGKGGRNPRV VVFGGEDRRG
RLLDDARVLD LTKMRWIEDE RTRTNKAPRG RGVKAPTWPA ARSGHVACCF GYGSPDVYVF
GGVKAGGAGE PTDELFCLNS MTMTWHRLNP AGVVPAPRTN SAGCVLDDGI WLIIGGGNGG
GGLADTVGLK LANPRGVGAN QVSGLEWFTA GEVQRGSALA AEGMTCVSVG GNPGECGAII
AFGGYDGRRY SNCTHAMRRP GRARMDTRGE TKPREAAHEV GDASGHSARS VASPGVVAAM
SRSNNGSAVS LRRVSSENSE IRRLRSENEA AKEALRRANE RLAELGAAPI DFVIGDESGS
GDKRSPPPPT RRRGLWAFIS GGDADDVDSG YDSPAR
//
