ID C1GG97_PARBD Unreviewed; 1270 AA.
AC C1GG97;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Inner centromere protein ARK-binding domain-containing protein {ECO:0000259|Pfam:PF03941};
GN ORFNames=PADG_06334 {ECO:0000313|EMBL:EEH50255.2};
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH50255.2, ECO:0000313|Proteomes:UP000001628};
RN [1] {ECO:0000313|EMBL:EEH50255.2, ECO:0000313|Proteomes:UP000001628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18 {ECO:0000313|EMBL:EEH50255.2,
RC ECO:0000313|Proteomes:UP000001628};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the INCENP family.
CC {ECO:0000256|ARBA:ARBA00010042}.
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DR EMBL; KN275964; EEH50255.2; -; Genomic_DNA.
DR RefSeq; XP_010761695.1; XM_010763393.1.
DR AlphaFoldDB; C1GG97; -.
DR STRING; 502780.C1GG97; -.
DR GeneID; 22585084; -.
DR KEGG; pbn:PADG_06334; -.
DR VEuPathDB; FungiDB:PADG_06334; -.
DR eggNOG; ENOG502S0AD; Eukaryota.
DR HOGENOM; CLU_003318_1_0_1; -.
DR InParanoid; C1GG97; -.
DR OMA; PVPKWAQ; -.
DR OrthoDB; 1368690at2759; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR InterPro; IPR005635; Inner_centromere_prot_ARK-bd.
DR PANTHER; PTHR13142; INNER CENTROMERE PROTEIN; 1.
DR PANTHER; PTHR13142:SF1; INNER CENTROMERE PROTEIN; 1.
DR Pfam; PF03941; INCENP_ARK-bind; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001628}.
FT DOMAIN 1166..1220
FT /note="Inner centromere protein ARK-binding"
FT /evidence="ECO:0000259|Pfam:PF03941"
FT REGION 175..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..1065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1082..1187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..416
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..725
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..765
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..800
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 881..951
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 952..974
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1001
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1050
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1131..1156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1270 AA; 140370 MW; 3DCF0ADB91C3D0BE CRC64;
MASTGTKARR AVGSSAWIAT ERENIDLLVS LEMEEIEYPA QHEMDWLNEH MAEIFNRSQL
NVTEIFKTPG KLRGKTPRTV RKHQTPREGR VPLSDIFAAG QNVRNSSGPP SRFNQEIAKL
SRKPSPNEHP KYSSPVQIQN PILNSIADSG YHSGYHDMAH EDEIADDDEM DLVYSQPQKE
PGSTTEQEPK GEETKPEAAL EPERSPEPER DPEFELETAA QPLEDSTIVV PRDRNDISPS
VDRRTTDASF HSAREVVPSK ESSTVEPLET DDCKSPPISV SKQPLSASPQ PSQESVQLPA
IFDFAPPETA NTIEPDSDVH DAALDHNFDD IGSPSDGSTP DRPPVRKSSL SFASLPAREP
LTTKRSIGGA RMSRISHIDP SKSIPGGYFG RQTGGARITQ ISPEEQDKRG NTGDNTTPEE
ERAPAFLPDE SDLGTKATNL HHKSSTQLLH EKINMLGKSQ PSRNTKSIPA PAPIAPSQVS
YPELLSQVDP VADKPRKPSP VEPQVCDNRT APPRSPQHFQ QPQSAGEPIA ESPQQLPRVQ
TQEERISRIM YSKSPERRSP GLKPVGISGI YHTKSASTSV ITSPRANTIG LQRATSNRAS
LTPVSSPRRD DGPLSASKSK LQSIMKTAKS LFTSSAGVSA AAKMETFSPT PIRTQANLYP
NLQENFTQAP QPAAIQSPIF QEGRRTRSST EREEKRKEKE RQDMERIEEQ LQKAREQERQ
QKTTMIKDVS QHQALPKSEE TVATPATHAM KSSPRRPPTQ QSLREAEQTQ EEEHKFAVPA
KPQHHPKQNE SRRPLRPTRE AQKPKPQPVS IRVGTLSQRI PLTNSSLSSI APDATPGPPP
APKALLSAVN KKGSQPSIHA NSSTSSFKSS TSMINSKSKA AQASEKKEAK QRREAERMRV
AQQQEEARRQ EQTGWAEADR RERERSVPED PKKLAHKQAI EKRRLENARK LEQQRNQQPT
PANDLGSTIH QEKSGLHGNQ RKDISSLKGP RLNSVQGQAR PMNYPHPNPA KPPKRVLEDE
SSGRPVTGKV GAAVHQADGK RRKTDDESVI AEPPVRPAMA PPIRQSNVRK EVSKLQMYNQ
GGQAIFKNPP ASRAPQGAVP IQQQPHRNGH PLEMSKFASG KIPFADNSNP PHAMSHKTPG
QGSQKPQISL KSSPAYPNGD SIKLPEILTD SEDEDSDAEP YNVPDWAKPE NLTNILISQE
GQDGAQVFGP SAPLHMEEIF KDNKDRLKRF RDRTSSANWG GPDGLTQAEI KWDIEQRERL
KKNGGWTFAP
//
