ID C1GKM4_PARBD Unreviewed; 432 AA.
AC C1GKM4;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Vta1 C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PADG_07810 {ECO:0000313|EMBL:EEH42990.1};
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH42990.1, ECO:0000313|Proteomes:UP000001628};
RN [1] {ECO:0000313|EMBL:EEH42990.1, ECO:0000313|Proteomes:UP000001628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18 {ECO:0000313|EMBL:EEH42990.1,
RC ECO:0000313|Proteomes:UP000001628};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Endosome membrane {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the VTA1 family.
CC {ECO:0000256|ARBA:ARBA00007895}.
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DR EMBL; KN275968; EEH42990.1; -; Genomic_DNA.
DR RefSeq; XP_010763161.1; XM_010764859.1.
DR AlphaFoldDB; C1GKM4; -.
DR STRING; 502780.C1GKM4; -.
DR GeneID; 22586234; -.
DR KEGG; pbn:PADG_07810; -.
DR VEuPathDB; FungiDB:PADG_07810; -.
DR eggNOG; KOG0917; Eukaryota.
DR HOGENOM; CLU_030378_0_0_1; -.
DR InParanoid; C1GKM4; -.
DR OMA; AYWCEYH; -.
DR OrthoDB; 5491267at2759; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.420; Immunoglobulin FC, subunit C; 1.
DR Gene3D; 1.25.40.270; Vacuolar protein sorting-associated protein vta1; 1.
DR InterPro; IPR044538; Vta1-like.
DR InterPro; IPR039431; Vta1/CALS_N.
DR InterPro; IPR023175; Vta1/CALS_N_sf.
DR InterPro; IPR041212; Vta1_C.
DR PANTHER; PTHR46009; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG; 1.
DR PANTHER; PTHR46009:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG; 1.
DR Pfam; PF04652; Vta1; 1.
DR Pfam; PF18097; Vta1_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 13..156
FT /note="Vta1/callose synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04652"
FT DOMAIN 393..430
FT /note="Vta1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18097"
FT REGION 158..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 432 AA; 46754 MW; EAB6478FE49B4D46 CRC64;
MAANIPAKLK AADITRFVTR ASQLEKARPV ISYWCNYWAV NQILSKGLHN SDSECLRYTT
ELMDKLEKFK SQHVDDDTVT DDAAGQAYVE QFGLETFQRA DNAVRANRAS LQTADTFQAA
ATFLELCQIW GPAEPEIATK IKFAKYHALR IAKALKAGED PNLSNPSREE EEMPNDVPSL
DPNDPEVQAL NNPSSQSAPE VKLRQPSVED VTDEFYNEEK RLAHQSSLNE SLHPSRASSV
PPFRRPESGI VTAASSTGLP SPPSYSAGMM DLSPDARQRP SHLSQAYVPD LPAAPSDFPS
PASSSQDLPA TGTGGFSERR TSLSTFQSFP APTTQPSTDI PGPAMGSPPP SGFDGWMRQA
PPTTAPPTSI QPTKPVQGAS SYPNQPPAHG VDEDAIAKAQ KHARWAVSAL NFDDVQTAIK
ELTNALNMLG SK
//
