ID   C1GKW4_PARBD            Unreviewed;       353 AA.
AC   C1GKW4;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=GDSL lipase/acylhydrolase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PADG_07971 {ECO:0000313|EMBL:EEH43151.1};
OS   Paracoccidioides brasiliensis (strain Pb18).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH43151.1, ECO:0000313|Proteomes:UP000001628};
RN   [1] {ECO:0000313|EMBL:EEH43151.1, ECO:0000313|Proteomes:UP000001628}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb18 {ECO:0000313|EMBL:EEH43151.1,
RC   ECO:0000313|Proteomes:UP000001628};
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; KN275969; EEH43151.1; -; Genomic_DNA.
DR   RefSeq; XP_010763352.1; XM_010765050.1.
DR   AlphaFoldDB; C1GKW4; -.
DR   STRING; 502780.C1GKW4; -.
DR   GeneID; 22586355; -.
DR   KEGG; pbn:PADG_07971; -.
DR   VEuPathDB; FungiDB:PADG_07971; -.
DR   eggNOG; ENOG502RY46; Eukaryota.
DR   HOGENOM; CLU_015101_1_0_1; -.
DR   InParanoid; C1GKW4; -.
DR   OMA; SYLWYDD; -.
DR   OrthoDB; 844729at2759; -.
DR   Proteomes; UP000001628; Unassembled WGS sequence.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   CDD; cd01846; fatty_acyltransferase_like; 1.
DR   Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR   InterPro; IPR001087; GDSL.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   PANTHER; PTHR45648; GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700); 1.
DR   PANTHER; PTHR45648:SF22; GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700); 1.
DR   Pfam; PF00657; Lipase_GDSL; 1.
DR   SUPFAM; SSF52266; SGNH hydrolase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..353
FT                   /note="GDSL lipase/acylhydrolase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002910130"
SQ   SEQUENCE   353 AA;  39791 MW;  778E85CFA9720873 CRC64;
     MAPGPRLAFA LGLGTWALSV HAHSAWNLRV MESLVAFGDS YTDESRLRYF IEHKERPPVG
     WIAPETRITS SGGTVWARYA SRYTGAQLYN YAVSGAVCSN DITPRFFGPT NSTFPSVEQY
     EIPAFMADAS FQDPATGIPF LNLPRRETVY AIWIGTNDLG NGAFMTDSQA AGTTLPDYVE
     CVFRSLDRLY DHGGLYFVLM NLAPLDLLPL YALPERGGVR RPPFCPNKPE NITEISYRMK
     QAVVAVNEIM KLKVEISMWH RYRGAGIALF DTHSLLSDMY FNPRRYLNGT KPPDIQGWIR
     HCDHRGQNCD DQPSPDSYMW YDELHPSEQT GRILAQHFVE VVKGTSAFAT YFS
//