ID C1GQ34_PARBA Unreviewed; 367 AA.
AC C1GQ34;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 2.
DT 03-MAY-2023, entry version 61.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:EEH36306.2};
GN ORFNames=PAAG_00629 {ECO:0000313|EMBL:EEH36306.2};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH36306.2, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH36306.2, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN293992; EEH36306.2; -; Genomic_DNA.
DR RefSeq; XP_015700418.1; XM_015844083.1.
DR AlphaFoldDB; C1GQ34; -.
DR STRING; 502779.C1GQ34; -.
DR GeneID; 9101313; -.
DR KEGG; pbl:PAAG_00629; -.
DR VEuPathDB; FungiDB:PAAG_00629; -.
DR eggNOG; KOG1198; Eukaryota.
DR HOGENOM; CLU_026673_3_4_1; -.
DR OMA; LNHHDLW; -.
DR OrthoDB; 2085300at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08276; MDR7; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR45033; -; 1.
DR PANTHER; PTHR45033:SF3; DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002059}.
FT DOMAIN 15..357
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 367 AA; 38785 MW; 18541BF4B188C6FE CRC64;
MPYSITIDPI DGKPGKPGQV YYPLALKTVP IPTPQGSELL IKLTAAALNH RDLFLRQHLY
PGVTFGVPLL ADGVGIVIST GPDVNEPQSW LGKRVILNPG TGWDDAEEGP ESPTAYSIMG
GTKLNPKGTL QEYVTLDIDE VIEAPTHLTD AEAAALPLAG LTGWRALVTK AGAKNSSKGA
AIVITGIGGG VALMVLKFAV ARGVHVIVTS ASEEKIKMAV ALGAKGGVNY KDNEWEKRAL
ALLPPGKKNF DAIIDGAGGN SIEKGVKLLK AGGVISVYGM TVSPKMPFIT PAFLKNIEVK
GSTMGSRKEF RQMIAFVNEH KIKPIISRVV QGIDNIKAID GLFDDMKNAS QFGKLVIEIG
STGDSKL
//
