ID C1GVB6_PARBA Unreviewed; 759 AA.
AC C1GVB6;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 22-FEB-2023, entry version 60.
DE RecName: Full=Enhancer of mRNA-decapping protein 3 {ECO:0000256|ARBA:ARBA00015797};
GN ORFNames=PAAG_02589 {ECO:0000313|EMBL:EEH40534.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH40534.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH40534.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the EDC3 family.
CC {ECO:0000256|ARBA:ARBA00006610}.
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DR EMBL; KN293996; EEH40534.1; -; Genomic_DNA.
DR RefSeq; XP_002795883.1; XM_002795837.1.
DR AlphaFoldDB; C1GVB6; -.
DR STRING; 502779.C1GVB6; -.
DR GeneID; 9098801; -.
DR KEGG; pbl:PAAG_02589; -.
DR VEuPathDB; FungiDB:PAAG_02589; -.
DR eggNOG; KOG2585; Eukaryota.
DR HOGENOM; CLU_024328_0_0_1; -.
DR OMA; AWRKYGT; -.
DR OrthoDB; 1409462at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.10260; YjeF N-terminal domain; 1.
DR InterPro; IPR025762; DFDF.
DR InterPro; IPR019050; FDF_dom.
DR InterPro; IPR004443; YjeF_N_dom.
DR InterPro; IPR036652; YjeF_N_dom_sf.
DR PANTHER; PTHR13612:SF0; ENHANCER OF MRNA-DECAPPING PROTEIN 3; 1.
DR PANTHER; PTHR13612; UNCHARACTERIZED; 1.
DR Pfam; PF09532; FDF; 1.
DR Pfam; PF03853; YjeF_N; 1.
DR SMART; SM01199; FDF; 1.
DR SUPFAM; SSF64153; YjeF N-terminal domain-like; 1.
DR PROSITE; PS51512; DFDF; 1.
DR PROSITE; PS51385; YJEF_N; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059}.
FT DOMAIN 327..363
FT /note="DFDF"
FT /evidence="ECO:0000259|PROSITE:PS51512"
FT DOMAIN 507..732
FT /note="YjeF N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51385"
FT REGION 129..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 759 AA; 82105 MW; 01AB938E701D0AE3 CRC64;
MAEDFVGYTV LVTLKSPPNS QVQGVVADVV GQRLTLKDVT LLWNGQRLPL YHIDAPGIAD
LELSSHQIPH HPIANNYGSG SPRTFLNGGP FLSQHHPSQP AQVRPENIAE ALSSESQRPR
FVDPAILSFQ KPSKPQPLST TNMPLPVSKR GSSPVMIADS ESIGRSGPIS TAPLTGKSVG
PKKTNTNDTA ATLSEPFNNL GFNAGEDSKE AQAGPVQKQE DLDIPEGRRG AGPLEAPLKY
TGKRSRRGGR NKLNKDAAVQ SSSIGPVLED PSATLSSTRT NIAGKGWRMT AFVEPGHPPS
PPKPGRTRRS KARSRKSHAD DASGWATEDA TDIQEMGDFD FATNLSKFDK RRIFDQIRND
DTTTGEERLV SFNRRGHRPG TNEGKNLHYT ENVLDDDTSH GKWNSEAGET EEDELSGECF
SSEKTSARAR SGVSARAQSR KRSTILGSTL VSSQISSLSR GQMTSSRTES PQPHRSSPRV
GSTSPAAGYL MLIPTNRECP CVAPLQMIEI EQLAISELGL GEDVISENAG RGIAEAAVSQ
IPKLATSSAI LVLAGNHRTG SRAVCAARHF RNRGYRVTLC VLGSDRENEL IEGVRKQVDI
FEKISGKVLR WEEMSTRLSA GDYVPDLVID ALFGVHIAFD DLRTDEQATA FEMISWANRS
NVEILSVDVP SGLSALSGEP TIVQGSRLNV NPKFIVCLAA PKTGLLQALG SGEGLAWNIT
VADIGISQVP WRKHGSRRRH GVDFGNQWVV PLRFELPTS
//
