ID C1GZJ1_PARBA Unreviewed; 362 AA.
AC C1GZJ1;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 22-FEB-2023, entry version 55.
DE SubName: Full=Mitotic spindle checkpoint protein (Mad2B) {ECO:0000313|EMBL:EEH42014.1};
GN ORFNames=PAAG_03935 {ECO:0000313|EMBL:EEH42014.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH42014.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH42014.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SIMILARITY: Belongs to the MAD2 family.
CC {ECO:0000256|ARBA:ARBA00010348}.
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DR EMBL; KN294000; EEH42014.1; -; Genomic_DNA.
DR RefSeq; XP_002794342.1; XM_002794296.2.
DR AlphaFoldDB; C1GZJ1; -.
DR STRING; 502779.C1GZJ1; -.
DR GeneID; 9097540; -.
DR KEGG; pbl:PAAG_03935; -.
DR VEuPathDB; FungiDB:PAAG_03935; -.
DR eggNOG; KOG3186; Eukaryota.
DR HOGENOM; CLU_050394_1_0_1; -.
DR OMA; KEEQTWI; -.
DR OrthoDB; 448945at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR PANTHER; PTHR11842:SF10; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002059}.
FT DOMAIN 82..343
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 39276 MW; 4EFBF9E3CD818D48 CRC64;
MAQTTSSPAN ADIGSSSSSF PHEALPAGPA SSPPHSAATN NNNAFQRHTN ATSTSSVISN
GNHNNTCHTH NHRPSQLPDT YAALTSSIAS FLAVSIHQIL YLRAIYPQST FLPVRHFNRP
VRQSRHPRVC TWITDACAAV EAQLLKCTIA AVSIVILSSS NNQPLERYTF DMTQIPEVPP
GDIHTPFDND NNNFIASEDP KNQQQQQQQQ QSTKTQTHIP PIELEAQFRA VLARLASACA
RLTPLPRNEE YIPTLHIVLR NTADAPAGIS NADHLWIAAE PSKLDLNGNC NSNNTANGCE
NSLSGKCAVG GVGEFDRAGS RGRAKTVPVR TVDAGELKME VWVEEAKGKF AELNRIRAVH
ES
//
