ID C1H2N8_PARBA Unreviewed; 384 AA.
AC C1H2N8;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=NADH-ubiquinone oxidoreductase 40 kDa subunit {ECO:0000313|EMBL:EEH33982.2};
GN ORFNames=PAAG_05031 {ECO:0000313|EMBL:EEH33982.2};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH33982.2, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH33982.2, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN294004; EEH33982.2; -; Genomic_DNA.
DR RefSeq; XP_015699673.1; XM_015845447.1.
DR AlphaFoldDB; C1H2N8; -.
DR STRING; 502779.C1H2N8; -.
DR GeneID; 9096274; -.
DR KEGG; pbl:PAAG_05031; -.
DR VEuPathDB; FungiDB:PAAG_05031; -.
DR eggNOG; KOG2865; Eukaryota.
DR HOGENOM; CLU_007383_6_4_1; -.
DR OMA; EDQFFNR; -.
DR OrthoDB; 141210at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR CDD; cd05271; NDUFA9_like_SDR_a; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR12126:SF11; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12126; NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW Ubiquinone {ECO:0000313|EMBL:EEH33982.2}.
FT DOMAIN 61..179
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 384 AA; 43968 MW; 7AEDD93F95622872 CRC64;
MQKCRAIQGA LGSRAVTPLP SVRAQPHIQR RNIQDVYITR TGTPIIKVQG GRSSIGGHTA
TVFGATGFLG RYIVNRLARQ GCTVVVPYRE EMAKRHLKVT GDLGRVVFME YDLRNTQSIE
ESVRHSDVVY NLVGRKYPTK NFSYEDVHID GLERIAEATA KYDVDRFIHV SSYNADPNSP
SEFFRTKARG EQLARSIFPE TTIVRPAPMF GFEDNLLHKL ASITNLFTSN HMQERYWPVH
VIDVGHALEK MMFTDASVGQ TYELYGPKNY STAEIAELVD REIIKKRRHL NVPKRIMKPA
AYWANRLLWW PAISADEVEM EFLDQQIDPS AKTFKDLDIE PAEISNLTFH YLQGYRSSQY
SDLPPASERE RAEEKKYLHV LDDQ
//
