ID C1H6H3_PARBA Unreviewed; 232 AA.
AC C1H6H3;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 2.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=Coenzyme Q-binding protein COQ10 START domain-containing protein {ECO:0000259|Pfam:PF03364};
GN ORFNames=PAAG_06364 {ECO:0000313|EMBL:EEH35317.2};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH35317.2, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH35317.2, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC chain. May serve as a chaperone or may be involved in the transport of
CC Q6 from its site of synthesis to the catalytic sites of the respiratory
CC complexes. {ECO:0000256|ARBA:ARBA00024947}.
CC -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000256|ARBA:ARBA00011814}.
CC -!- SIMILARITY: Belongs to the COQ10 family.
CC {ECO:0000256|ARBA:ARBA00006885}.
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DR EMBL; KN294009; EEH35317.2; -; Genomic_DNA.
DR RefSeq; XP_015700096.1; XM_015845870.1.
DR AlphaFoldDB; C1H6H3; -.
DR STRING; 502779.C1H6H3; -.
DR GeneID; 9094906; -.
DR KEGG; pbl:PAAG_06364; -.
DR VEuPathDB; FungiDB:PAAG_06364; -.
DR eggNOG; KOG3177; Eukaryota.
DR HOGENOM; CLU_079653_1_0_1; -.
DR OMA; QLHAAMM; -.
DR OrthoDB; 2722348at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0048039; F:ubiquinone binding; IEA:InterPro.
DR GO; GO:0045333; P:cellular respiration; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro.
DR CDD; cd07813; COQ10p_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR044996; COQ10-like.
DR InterPro; IPR005031; COQ10_START.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR12901:SF10; COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12901; SPERM PROTEIN HOMOLOG; 1.
DR Pfam; PF03364; Polyketide_cyc; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002059}.
FT DOMAIN 56..222
FT /note="Coenzyme Q-binding protein COQ10 START"
FT /evidence="ECO:0000259|Pfam:PF03364"
FT REGION 126..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 25325 MW; 9B8C18DD518D46DA CRC64;
MHPPSPLLRL LLLPKQPPRR TGTITKPPSH NFHLPTFATA FYPPPPRTLT AARNLPFPPE
PLFRTISDID SYARFLPFLT ASTVTARDGE TGYPTSAFLT VGYGPLSETF VSRVECDGER
WTVGARSGWG GNGNGNGNGN GSGRGGDGGD GGLFEYLDTL WKLQPLRPRD HGHGHGHVRI
GGGREETKVV LEVRFQFRSA MHAAMMGAVE SQVAGMMIEA FEKRVRELDM AK
//
