ID C1H933_PARBA Unreviewed; 1105 AA.
AC C1H933;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 22-FEB-2023, entry version 56.
DE RecName: Full=Vacuolar protein sorting-associated protein 54 C-terminal domain-containing protein {ECO:0000259|Pfam:PF07928};
GN ORFNames=PAAG_07274 {ECO:0000313|EMBL:EEH36856.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH36856.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH36856.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SIMILARITY: Belongs to the VPS54 family.
CC {ECO:0000256|ARBA:ARBA00009150}.
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DR EMBL; KN294014; EEH36856.1; -; Genomic_DNA.
DR RefSeq; XP_002790737.1; XM_002790691.1.
DR AlphaFoldDB; C1H933; -.
DR STRING; 502779.C1H933; -.
DR GeneID; 9093941; -.
DR KEGG; pbl:PAAG_07274; -.
DR VEuPathDB; FungiDB:PAAG_07274; -.
DR eggNOG; KOG2115; Eukaryota.
DR HOGENOM; CLU_003094_1_0_1; -.
DR OMA; FSFVQSY; -.
DR OrthoDB; 38119at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0000938; C:GARP complex; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR Gene3D; 6.10.250.860; -; 1.
DR InterPro; IPR039745; Vps54.
DR InterPro; IPR012501; Vps54_C.
DR PANTHER; PTHR12965; VACUOLAR PROTEIN SORTING 54; 1.
DR PANTHER; PTHR12965:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54; 1.
DR Pfam; PF07928; Vps54; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 822..953
FT /note="Vacuolar protein sorting-associated protein 54 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07928"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1066..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..806
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1105 AA; 121962 MW; 7CC21F7991AEE5CA CRC64;
MTSSDKRKSV ESLASLSSVS LATQPSSSSQ YDPGRLPQRL RYNSRRSSTA SSISGIGSAL
DTSLHHGSIA EAGRNAISTL LQQPIVRTGL LPQASALSSG YKPPTTRDIP PVALTNIPHV
ESKAFQPYIS QVGSLYDALR RSKENGDEGE PQLRRASSTT TISVDIDPLL SSQLERRHSG
QHTPLSSVSE YVTPRRRSAG QRGRGPAMAP LSTIPNVYFD ENFHLENPRT FDVVSERSEV
VRSPPKPSDE NAPNGSFEAR PAFNRKALAT NAILQEKLSW YLDTVEIHLI SSISNASTSF
FTALGSLQAL HGEAKASVDK IQALRRDLAK LDNDMALGGL KVVNLRRRRE NVRKLADAVC
QLKVIIACVS HCEQMVENGD IENALDELDH VERLTAGERT ATKREDRGGQ SQLPETLIDL
RGIKALEGAS DDLGQLRSRI GIGYEQRFLD CLIGDIKRHV ESLPPELTLL RLGDAFHRSR
RTHRKAPSSI PTYMTIDNEF RSRLKSELVG LGRARYTTSA ATSYKNSVLR EMKSSIRRHL
PSSSDDDNES IMSASTHGDR QLNQQEKSTI LARNLRALDP EDAYAMLTKI YTGVSEFLRR
LSIQVKVLLD ITSGLSSPPN TSGVRSPLQS PNLHSIDAYV RSGTTPVAAQ EEVMEILDMS
SLLGQAVDIV QSQMVKILKI RSEQTAHLSL EQFLKYFSLN KLFADECEAI SGRSGSALKN
VVDSQIRDFI SNFGDSRKHR LVQVMDSDRW DAKDFGDKQN ALLSRILQAS TQDIDLWAST
SRVWESDHSG QETTATQDSP EVNGNGVTDS GKDKVRSAIV DEQKYILPQS ALLILEIIDE
FQHLMTGIPS MVQDIAFNFL ECLKLFNSRS SQLILGAGAT RSAGLKNITT KHLALASQAL
SFIIALIPHV REFIRRHYTS TTTLMAEFDK VKRLCQEHQS GIHEKLVDIM SSRATIHVNA
MKKIDWDAQQ DTASVSPYMK TLTKETGTLQ RVLTKHLPEM TVMMIMDPVF KSYRDQWTRA
FQAATLKTEG GKQRMVSDVE YFKAKIDKID GSGDLGNHLV EVVKSKSVAS PPKPDSPLPP
AEAQPAESSP QKGDKNGAPI PDQGS
//
