ID C1IMY4_9ACTO Unreviewed; 168 AA.
AC C1IMY4;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Methionyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030904};
DE Flags: Fragment;
GN Name=metG {ECO:0000313|EMBL:ACF21428.1};
OS Actinomyces oris.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=544580 {ECO:0000313|EMBL:ACF21428.1};
RN [1] {ECO:0000313|EMBL:ACF21428.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=M47-1-1 {ECO:0000313|EMBL:ACF21428.1};
RA Henssge U., Do T., Radford D.R., Gilbert S.C., Clark D., Beighton D.;
RT "Emended description of Actinomyces naeslundii and descriptions of
RT Actinomyces oris sp. nov. and Actinomyces johnsonii sp. nov., previously
RT identified as Actinomyces naeslundii genospecies 1, 2 and WVA 963.";
RL Int. J. Syst. Evol. Microbiol. 59:509-516(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-
CC methionyl-tRNA(Met); Xref=Rhea:RHEA:13481, Rhea:RHEA-COMP:9667,
CC Rhea:RHEA-COMP:9698, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:57844, ChEBI:CHEBI:78442, ChEBI:CHEBI:78530,
CC ChEBI:CHEBI:456215; EC=6.1.1.10;
CC Evidence={ECO:0000256|ARBA:ARBA00001234};
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC MetG type 1 subfamily. {ECO:0000256|ARBA:ARBA00008258}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EU621193; ACF21428.1; -; Genomic_DNA.
DR AlphaFoldDB; C1IMY4; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
DR CDD; cd07957; Anticodon_Ia_Met; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR041872; Anticodon_Met.
DR InterPro; IPR023458; Met-tRNA_ligase_1.
DR InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR PANTHER; PTHR45765; METHIONINE--TRNA LIGASE; 1.
DR PANTHER; PTHR45765:SF1; METHIONINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR Pfam; PF09334; tRNA-synt_1g; 1.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:ACF21428.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 1..71
FT /note="Methionyl/Leucyl tRNA synthetase"
FT /evidence="ECO:0000259|Pfam:PF09334"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACF21428.1"
FT NON_TER 168
FT /evidence="ECO:0000313|EMBL:ACF21428.1"
SQ SEQUENCE 168 AA; 18558 MW; A0BCAF640542FE2D CRC64;
FLTMEGKKFS SSHGIVIYVR DFLERYQADA LRYFICAAGP ETADADFTWA EFVRRTNGEL
VAGWGNLVNR TASMIHKRFG QIPEPAELQD IDRALLDAVE AGFASVGEFI AQHRQKAALG
EAMRLVGEAN KYVADTQPFK LKGEDPATQA RLATVLHTLA QAVTDLNL
//
