ID C1L8S8_SCHJA Unreviewed; 180 AA.
AC C1L8S8;
DT 03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE RecName: Full=Translocon-associated protein subunit beta {ECO:0000256|ARBA:ARBA00021110, ECO:0000256|PIRNR:PIRNR016400};
DE Short=TRAP-beta {ECO:0000256|PIRNR:PIRNR016400};
DE AltName: Full=Signal sequence receptor subunit beta {ECO:0000256|PIRNR:PIRNR016400};
GN Name=TRAP-beta {ECO:0000313|EMBL:CAX71106.1};
OS Schistosoma japonicum (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6182 {ECO:0000313|EMBL:CAX71106.1};
RN [1] {ECO:0000313|EMBL:CAX71106.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Anhui {ECO:0000313|EMBL:CAX71106.1};
RX DOI=10.1038/nature08140;
RA Liu F., Zhou Y., Wang Z.Q., Lu G., Zheng H., Brindley P.J., McManus D.P.,
RA Blair D., Zhang Q.H., Zhong Y., Wang S., Han Z.G., Chen Z.;
RT "The Schistosoma japonicum genome reveals features of host-parasite
RT interplay.";
RL Nature 460:345-351(2009).
RN [2] {ECO:0000313|EMBL:CAX71106.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Anhui {ECO:0000313|EMBL:CAX71106.1};
RA Gang L.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: TRAP proteins are part of a complex whose function is to bind
CC calcium to the ER membrane and thereby regulate the retention of ER
CC resident proteins. {ECO:0000256|ARBA:ARBA00002838,
CC ECO:0000256|PIRNR:PIRNR016400}.
CC -!- SUBUNIT: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-
CC gamma. {ECO:0000256|PIRNR:PIRNR016400}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the TRAP-beta family.
CC {ECO:0000256|ARBA:ARBA00005610, ECO:0000256|PIRNR:PIRNR016400}.
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DR EMBL; FN315374; CAX71106.1; -; mRNA.
DR AlphaFoldDB; C1L8S8; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008856; TRAP_beta.
DR PANTHER; PTHR12861:SF3; TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA; 1.
DR PANTHER; PTHR12861; TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT; 1.
DR Pfam; PF05753; TRAP_beta; 1.
DR PIRSF; PIRSF016400; TRAP_beta; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|PIRNR:PIRNR016400};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR016400};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..180
FT /note="Translocon-associated protein subunit beta"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002911416"
FT TRANSMEM 155..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 180 AA; 20364 MW; BB0F86FA4DB249B2 CRC64;
MLTLYLSALM AVFLVVSVSS DSGDNVRLVV SKEILNEFIF EEKEMTVLYT IYNFHESRAA
RDVELLDTFA ETEFTLIHGS PSARWSVIPA SSNVAHVLIL KPQINGFHNF SSATITYKSN
DLLDSALLYS SSPGLLTIHK LKEYNKRFTS HTMEWIGFAL FVTPCLLIPY MLWHSSASKY
//
