ID   C1LJI3_SCHJA            Unreviewed;       450 AA.
AC   C1LJI3;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   22-FEB-2023, entry version 31.
DE   SubName: Full=ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein) (GAP protein) {ECO:0000313|EMBL:CAX74861.1};
OS   Schistosoma japonicum (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6182 {ECO:0000313|EMBL:CAX74861.1};
RN   [1] {ECO:0000313|EMBL:CAX74861.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Anhui {ECO:0000313|EMBL:CAX74861.1};
RX   DOI=10.1038/nature08140;
RA   Liu F., Zhou Y., Wang Z.Q., Lu G., Zheng H., Brindley P.J., McManus D.P.,
RA   Blair D., Zhang Q.H., Zhong Y., Wang S., Han Z.G., Chen Z.;
RT   "The Schistosoma japonicum genome reveals features of host-parasite
RT   interplay.";
RL   Nature 460:345-351(2009).
RN   [2] {ECO:0000313|EMBL:CAX74861.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Anhui {ECO:0000313|EMBL:CAX74861.1};
RA   Gang L.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FN319133; CAX74861.1; -; mRNA.
DR   AlphaFoldDB; C1LJI3; -.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   CDD; cd08830; ArfGap_ArfGap1; 1.
DR   Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   PANTHER; PTHR46395; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR   PANTHER; PTHR46395:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT   DOMAIN          7..124
FT                   /note="Arf-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50115"
FT   REGION          345..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          406..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..373
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        406..423
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        424..442
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   450 AA;  50609 MW;  E087E46EA12F7A49 CRC64;
     MASPRTRRVL MDVKKTNTNH LCFECGSPNP QWASVTYGIW ICLECSGKHR GLGVHLSFVR
     SINMDKWKEL ELEKMRVGGN KHAKEFFTSQ PDYRPHWSFQ EKYNSKAAAL LRDKVATEAS
     GEHWDEATAT VRYNKPASIN HVKTTSDLPS LSSDKRNWSN NNNCDEYQTS DCNLRPNKMT
     SCQSDLESWL RNTNLSEEPG LSTTATTHTI TTSRYDQVPD WAKSMGNPEF ESSSSRHYSL
     VPQRNDKSSW QSGWEMVSQV ASVAAKCTSQ LASQATQKTK ELTQSVHEKV KDSNILDSLS
     KGVDTVTSKL QTVKTQGMRS FESYWSSNPD SDLSAGNFDK SYGSARLSTH EQSRSDSTFS
     DSYRRHGTDS SFDAGDRKGF SMSNPNWDSS ETCDWDLSDN HGWGSSIDDN WSTGGVKSSR
     KTTLASHSDI RRDSKLEKNN NVSNRSRKNS
//