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Database: UniProt
Entry: C1MRT5_MICPC
LinkDB: C1MRT5_MICPC
Original site: C1MRT5_MICPC 
ID   C1MRT5_MICPC            Unreviewed;       808 AA.
AC   C1MRT5;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   07-JUN-2017, entry version 27.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=MICPUCDRAFT_16972 {ECO:0000313|EMBL:EEH57384.1};
OS   Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC   Eukaryota; Viridiplantae; Chlorophyta; prasinophytes; Mamiellophyceae;
OC   Mamiellales; Mamiellaceae; Micromonas.
OX   NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN   [1] {ECO:0000313|EMBL:EEH57384.1, ECO:0000313|Proteomes:UP000001876}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH57384.1,
RC   ECO:0000313|Proteomes:UP000001876};
RX   PubMed=19359590; DOI=10.1126/science.1167222;
RA   Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA   Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA   Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA   Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA   Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W.,
RA   Gready J.E., John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F.,
RA   Moreau H., Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I.,
RA   Piegu B., Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T.,
RA   Zelensky A., Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W.,
RA   Van de Peer Y., Grigoriev I.V.;
RT   "Green evolution and dynamic adaptations revealed by genomes of the
RT   marine picoeukaryotes Micromonas.";
RL   Science 324:268-272(2009).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; GG663739; EEH57384.1; -; Genomic_DNA.
DR   RefSeq; XP_003058929.1; XM_003058883.1.
DR   GeneID; 9684005; -.
DR   KEGG; mpp:MICPUCDRAFT_16972; -.
DR   KO; K02154; -.
DR   OMA; TIPSFMN; -.
DR   Proteomes; UP000001876; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 2.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001876};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001876};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    402    426       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    446    464       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    531    552       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    564    587       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    633    651       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    742    762       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   808 AA;  89487 MW;  BBBADC5C75CE60DE CRC64;
     MELFRSESME LVRLIVPSEA SRDTVACSGD VGLVQFRDLN HAKPFPQRAY TYASRVKRCD
     EMLRRLRFFA AAFKDAGIAP RAMPSPETSI DFDDLETRLT EAESETRTMS AAIERLRRNR
     AELVELQVVT EKARAFFDEA TDGAGGLEIL GDDALLASAD DDVEKASRLG FIAGCVRASE
     APALERMAFR ATRGNLLFER ETIEGEMEDP ATGDFVVKTA FLVFFSGQHA RDAIAKIADS
     FGANRYPLQE DFSRRRRMRA EVAARETDLQ QTLRASTAHR DDLLRGIARA HAAWTTFVRK
     QKATYHALNM FSVDVARDVV VAEAWCPTFA KPAVRDALLR ANRSSSALVG TIFQPLASKE
     EPPTYFRTNK VTAAFQGIVD AYGIARYKEV NPTVLTIVTF PFLFAVMFGD FGHGILMLLA
     AMYMVLNEET LGATPQNEIF QMAFDGRYVV LLMSIFSMYA GAMYNECFSV PMTWLAGKTR
     WVCDANDATK GCDSQYVAGL ERNGTYAFGV DPIWRGSKSE LPFLNSMKMK MSIIMGVTQM
     MVGIFMSLLN FVRAKDVLSI ACECIPQVIF LGALFGYLVF LIVLKWITPG CEADLYHVLI
     YMFLDPGNVD CAGEGPGGTA GCPENVMFRG QGVLQVCLVV VAFASVPVML LPKPLVLKRR
     HDARARGEAY ARLPGEDEDG EAFNFGDVFV HQMIHTIEFV LGAVSNTASY LRLWALSLAH
     SQLSAVFLDR VLMASAATKS PLVMLVGFAV WAVATIGVLM LMESLSAFLH ALRLHWVEYQ
     NKFYKGDGYA FDPFSFESIL KEAAAEGS
//
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